Abstract
Twenty symptom-producing epimacular membranes removed during vitreous surgery were examined by light microscopy, scanning and transmission electron microscopy. These membranes contain cells of glial and pigment epithelial origin, but one also finds myofibroblasts and fibroblasts which cannot be identified morphologically as to their origin. The membranes can be classified into two types. Membranes in one group are composed of numerous alternating layers of collagen and cells and some internal limiting lamina. The second type of membrane is generally composed of a single layer of cells with large sheets of internal limiting lamina from the retinal surface and little if any collagen. Both types of membranes have cells on the retinal side of the removed internal limiting lamina, presumably derived from neurosensory retina.
Zusammenfassung
20 symptomatische epimakuläre Membranen wurden mikrochirurgisch entfernt und histologisch, elektronenmikroskopisch und mit dem Rasterelektronenmikroskop untersucht. Die Membranen enthalten Zellen gliösen und pigmentepithelialen Ursprungs sowie Fibroblasten und Myofibroblasten. Die Membranen können in zwei Gruppen eingeteilt werden. Die erste Gruppe enthält abwechselnd Schichten von Kollagen und Zellen sowie Lamina limitans interna. Die zweite Gruppe besteht aus einer Lage von Zellen ohne Kollagen aber mit riesigen Stücken der Lamina limitans interna. In beiden Gruppen findet man Zellen auf der retinalen Seite der Lamina limitans interna, die wahrscheinlich von der Retina selbst stammen.
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Supported by the National Institute of Health, no. EY02903, Helena Rubinstein Foundation, New York, New York; and Research to Prevent Blindness, Inc., New York, New York
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Trese, M., Chandler, D.B. & Machemer, R. Macular pucker. Graefe's Arch Clin Exp Ophthalmol 221, 16–26 (1983). https://doi.org/10.1007/BF02171726
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DOI: https://doi.org/10.1007/BF02171726