Summary
Nine representativeDl-amino acids were resolved using ligand-exchange chromatography whose mobile phase containe Cu (II) and ribonucleic acids. It was also found that deoxyribonucleic acids could be substituted for RNAs. In the presence of 5′-GMP, 4XMP, (a mixture of 5′-GMP,-AMP,-CMP, and-UMP), and oligomer of RNA,L-amino acids, which seemed to give more stable complexes, were eluted more slowly than the opposite isomers.
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Fukuhara, T., Yuasa, S. Ligand-exchange chromatographic resolution ofDl-amino acids in the presence of nucleic acids. J Mol Evol 32, 304–309 (1991). https://doi.org/10.1007/BF02102188
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DOI: https://doi.org/10.1007/BF02102188