Summary
The present work deals with the processes involved in the abiogenic polycondensation of nucleotides adsorbed on the clay mineral kaolinite under the action of ultraviolet (UV) radiation. The dependence of the yield of synthesis products on irradiation dose was studied. The maximum yield corresponds to a 6-h exposure. The newly synthesized substances were analyzed by ion-exchange chromatography. Some fractions were studied for the type of bonds they contained by venom phosphodiesterase and RNase T2 enzymatic hydrolysis. It was determined that some of the products synthesized by exposure of AMP adsorbed on the surface of clay particles to UV radiation may be looked upon as oligonucleotides in which some fragments have 2′–5′-bonded and others 3′–5′-bonded nucleotides
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References
Bernal JD (1951) The physical basis of life. Routledge, London
Ferris JP, Usher D (1983) Origins of life. In: Zubay G (ed) Biochemistry. Addison-Wesley, Boston, pp 1190
Gaustad JE, Vogel SN (1982) High energy solar radiation and the origins of life. Orig Life 12:3–8
Ibanez JD, Kimball AP, Oro J (1971) Possible prebiotic condensation of mononucleotides by cyanamide. Science 173:444–446
McReynolds JH, Forlong NB, Birrell PJ, Kimball AP, Oro J (1971) Polymerization of deoxyribonucleotides by ultraviolet light. In: Kimball AP, Oro J (eds) Prebiotic and biochemical evolution. North Holland, Amsterdam, London, pp 111–121
Otroshchenko VA, Vasilyeva NV, Kopilov AM (1985) Abiotic formation of oligonucleotides on basalt surfaces. Orig Life 15:115–120
Otroshchenko VA, Larventiev GA, Strigunkova TF (in press) Oligonucleotide formation on the mineral surface irradiated with gamma rays. Schtudia Biophisica
Rao M, Odom DG, Oro J (1980) Clays in, prebiological chemistry. J Mol Evol 15:317–331
Rishpon J, O'Hara PJ, Lahav N, Lawless JG (1982) Interaction between ATP, metal ions, glycine and several minerals. J Mol Evol 18:179–184
Rushizky GW, Sober HA (1962) Desalting of mono- and oligonucleotides. Biochim Biophys Acta 55:217
Schwartz AW (1981) Chemical evolution. In: Durama EK, Dawson R (eds) Marine organic chemistry. Elsevier, Amsterdam, pp 7–30
Tomlinson RV, Tener GM (1962) The use of urea to eliminate the secondary binding forces in ion exchange chromatography of polynucleotides. J Am Chem Soc 84:2644–2645
Walstrum SA, Usher DA (1983) Coupling reactions of oligonucleotides on complementary templates and rates of cleavage of the 2′–5′ and 3′–5′internucleotide bonds. In: 7th International conference on the origins of life and 4th meeting of the International Society for the Study of the Origins of Life, Mainz, Federal Republic of Germany, Abstracts C 2–23
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Strigunkova, T.F., Lavrentiev, G.A. & Otroshchenko, V.A. Abiogenic synthesis of oligonucleotides on kaolinite under the action of ultraviolet radiation. J Mol Evol 23, 290–293 (1986). https://doi.org/10.1007/BF02100636
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DOI: https://doi.org/10.1007/BF02100636