Abstract
Parameters of linear measurement were compared with actual brain volume to assess the significance of linear measurements as indices of atrophy in 31 neurologically normal children and 22 neurologically abnormal children. Brain volume was established by means of an image-analyzing system using contiguous CT scans. The parameters or indices estimated were: (1) the maximum transverse width of both hemispheres, (2) the maximum longitudinal length of both hemisphere, (3) the maximum frontal subarachnoid space, (4) the maximum width of the interhemsipheric fissure, (5) the maximum width of the Sylvian fissure, (6) Evan's ratio, (7) the maximum width of the third ventricle, (8) the cella media index, (9) the maximum width of the fourth ventricle. In neurologically normal children, the maximum transverse width of both hemispheres, the maximum longitudinal length of both hemispheres, the maximum width of the interhemispheric fissure and the maximum width of the Sylvian fissure correlated significantly with the combined volume (CV) of both hemispheres and basal ganglia. In particular, the maximum transverse width of both hemispheres and the maximum longitudinal length of both hemispheres had a high correlation. In neurologically abnormal children the maximum transverse width of both hemispheres and the maximum width of the interhemispheric fissure were significantly correlated with the CV of both hemispheres and basal ganglia.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Fukuyama Y, Miyao M, Ishizu T, Maruyama H (1979) Developmental changes in normal cranial measurements by computed tomography. Dev Med Child Neurol 21: 425
Okuma Y, Nishimiya J, Narabayashi H, Inoue R, Kuru Y (1988) Visibility of the inferior horns in computed tomography of normal subjects and epileptics. Brain Nerve (Tokyo) 40: 233
Hamano K, Iwasaki N, Kawashima K, Takita H (1990) Volumetric quantification of brain volume in children using sequential CT scans. Neuroradiology 32: 300
Gyldensted C, Kosteljanetz M (1976) Measurements of the normal ventricular system with computer tomography of the brain: a preliminary study of 44 adults. Neuroradiology 10: 147
Hahn FJY, Rim K (1976) Frontal ventricular dimensions of normal computed tomography. AJR 126: 593
Haug G (1977) Age and sex dependence of the size of normal ventricles on computed tomography. Neuroradiology 14: 201
Heinz ER, Ward A, Drayer BP, Dubois PJ (1980) Distinction between obstructive and atrophic dilatation of ventricles in children. J Comput Assist Tomogr 4: 320
Meese W, Kluge W, Grumme T, Hopfenmuller W (1980) CT evaluation of the CSF spaces of healthy persons. Neuroradiology 19: 131
Synek V, Reuben JR (1976) The ventricular-brain ratio using planimetric measurement of EMI scans. Br J Radiol 49: 233
Barron SA, Jacobs L, Kinkel WA (1976) Changes in size of normal lateral ventricles during aging determined by computerized tomography. Neurology 26: 1011
Thaler HT, Ferber PW, Rottenberg DA (1978) A statistical method for determining the proportions of gray matter, white matter and CSF using computed tomography. Neuroradiology 16: 133
Dufresne CR, McCarthy JG, Cutting CB, Epstein FJ, Hoffman WY (1987) Volumetric quantification of intracranial and ventricular volume following cranial vault remodeling: a preliminary report. Plast Reconstr Surg 79: 24
Gooskens RHJM, Gielen CCAM, Hanlo PW, Faber JA, Willemse J (1988) Intracranial spaces in childhood macrocephaly: comparison of length measurements and volume calculations. Dev Med Child Neurol 30: 509
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hamano, K., Iwasaki, N., Takeya, T. et al. A comparative study of linear measurement of the brain and three-dimensional measurement of brain volume using CT scans. Pediatr Radiol 23, 165–168 (1993). https://doi.org/10.1007/BF02013822
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02013822