Abstract
Using a panel of somatic rodent-human cell hybrids, we show that the interleukin-1 receptor antagonist gene (IL-1RN) maps to the long arm of human chromosome 2. Linkage studies permitted the regional localization of this gene to band q14-21. This is the same region in which the IL-1α and IL-1β genes are localized. Three yeast artificial chromosome (YAC) clones containing the IL-1RN gene were isolated, and these will be used for further characterization of this chromosome 2 region.
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Steinkasserer, A., Spurr, N.K. & Sim, R.B. Chromosomal mapping of the human interleukin-1 receptor antagonist gene (IL-1RN) and isolation of specific YAC clones. Agents and Actions 38 (Suppl 2), C59–C60 (1993). https://doi.org/10.1007/BF01991137
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DOI: https://doi.org/10.1007/BF01991137