Summary
We have built the phylogenetic tree of Vertebrate 5S RNA using the sequence data of thirteen species belonging to six groups. Evolution of the 5S genes has been very slow in Vertebrates since 90 residues are identical in all 5S RNAs which are presently sequenced.
In Amphibians and Teleosts different 5S genes are active in oocytes and in somatic cells. This dual gene system has probably been acquired independently by Amphibians and Teleosts. In Amphibians, the oocyte-type 5S genes have evolved much faster than the somatic-type genes. This is not true in all species since the oocyte-type genes of one Teleost (Tinca tinca) have evolved more slowly than the somatic-type genes.
There are in all Vertebrate 5S RNAs five complementary regions which can be base-paired. The sequence data are compatible with the three secondary-structure models that have been proposed for 5S RNA.
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References
Averner, M.J., Pace, N.R. (1972). J. Biol. Chem.247, 4491–4493
Bisbee, C.A., Baker, M.A., Wilson, A.C., Hadji-Azimi, I., Fischberg, M. (1977). Science195, 785–787
Brown, D.D., Caroll, D., Brown, R.D. (1977). Cell12, 1045–1056
Brownlee, G.G., Cartwright, E.M. (1975). Nucleic Acids Res.2, 2279–2288
Brownlee, G.G., Cartwright, E., McShane, T., Williamson, R. (1972). FEBS Letters25, 8–12
Denis, H., Wegnez, M. (1977). Develop. Biol.59, 228–236
Eck, R.V., Dayhoff, M.O. (1966). Atlas of protein sequence and structure. National Biomedical Research Foundation, Silver Spring
Ford, P.J., Brown, R.D. (1976). Cell8, 485–493
Ford, P.J., Southern, E.M. (1973). Nature New Biol.241, 7–12
Forget, B.G., Weissman, S.M. (1969). J. Biol. Chem.244, 3148–3165
Fox, G.E., Woese, C.R. (1975). Nature256, 505–507
Hori, H. (1976). Molec. Gen. Genet.145, 119–123
Pace, N.R., Walker, T.A., Pace, B. Erikson, R.L. (1974). J. Mol. Evol.3, 151–159
Roy, K.L. (1977). FEBS Letters80, 266–270
Roy, K.L., Enns, L. (1976). J. Biol. Chem.251, 6352–6354
Stambrook, P., Williamson, R. (1974). Eur. J. Biochem.48, 297–302
Vigne, R., Jordan, B.R. (1977). J. Mol. Evol.10, 77–86
Walker, T.A., Betz, J.L., Olah, J., Pace, N.R. (1975). FEBS Letters,54, 241–244
Wegnez, M., Denis, H., Mazabraud, A., Clérot, J.C. (1978). Develop. Biol.62, 99–111
Wegnez, M., Monier, R., Denis, H. (1972). FEBS Letters25, 13–20
Williamson, R., Brownlee, G.G. (1969). FEBS Letters3, 306–308
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Denis, H., Wegnez, M. Evolution of the 5 S RNA genes in vertebrates. J Mol Evol 12, 11–15 (1978). https://doi.org/10.1007/BF01732542
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DOI: https://doi.org/10.1007/BF01732542