Summary
The formation of glycerol occurs when a solution of DL-glyceraldehyde is heated in the presence of hydrogen sulfide at room temperature. DL-glyceraldehyde and dihydroxyacetone treated with hydrazine, as well as DL-glyceraldehyde incubated with formaldehyde are also partially converted to glycerol. The yields of the above reactions are from approximately 1% to about 3%. The formation of glycerophosphates occurs when glycerol is heated with ammonium dihydrogen phosphate and either urea or cyanamide. The yield of glycerophosphates is about 30%, most of which issn-glycero-1 (3)-phosphate. These findings indicate that glycerol andsn-glycero-3-phosphate, which are moieties of glycerolipids, could have been formed under conditions which may have prevailed on the primitive Earth.
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References
Chang, Y.Y., Kennedy, E.P. (1967). J. Lipid Res.8, 447–455
Eichberg, J., Sherwood, E., Epps, D.E., Oró, J. (1977). J. Mol. Evol.10, 221–230
Epps, D.E., Sherwood, E., Eichberg, J., Oró, J. (1978). J. Mol. Evol.11, 279–292
Hanes, C.S., Isherwood, F.A. (1949). Nature164, 1107–1112
Lapidot, Y., Barzilay, I., Hadju, J. (1969). Chem. Phys. Lipids3, 125–134
Lohrmann, R., Orgel, L.E. (1971). Science171, 490–494
Oró, J., Sherwood, E., Eichberg, J., Epps, D.E. (1978). In: Light transducing membranes (D. Deamer, ed.) pp. 1–19, New York, Academic Press
Schendel, P.F., Wells, R.D. (1973). J. Biol. Chem.248, 8319–8321
Schwartz, A.W. (1972). Biochem. Biophys. Acta281, 477–480
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Epps, D.E., Nooner, D.W., Eichberg, J. et al. Cyanamide mediated synthesis under plausible primitive earth conditions. J Mol Evol 14, 235–241 (1979). https://doi.org/10.1007/BF01732490
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DOI: https://doi.org/10.1007/BF01732490