Summary
The relationship between amino acid substitution and charge change of proteins in the evolutionary process is studied by using a stochastic model. A mathematical formula is developed for the electrophoretic identity of proteins between two different taxa for a given number of average codon differences per protein locus. Using this formula, a reference figure is constructed for estimating the average number of codon differences per locus between taxa.
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Dayhoff, M. O., Eck, R. V., Park, C. V.: In: Atlas of protein sequence and structure. Dayhoff, M. W., Ed., p. 75. Washington, D.C.: The National Research Foundation 1969
Feller, W.: An introduction to probability theory and its applications, Vol. I, 3rd Ed. New York: Wiley 1968
Henning, U., Yanofsky, C.: J. Molec. Biol.6, 16 (1963)
Kimura, M.: Genet. Res.11, 247 (1968)
King, J. L.: J. molec. Evolution2, 317 (1973)
Nei, M.: American Naturalist105, 385 (1971)
Nei, M.: American Naturalist106, 283 (1972)
Shaw, C. R.: Biochemical Genet.4, 275 (1970)
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Nei, M., Chakraborty, R. Genetic distance and electrophoretic identity of proteins between taxa. J Mol Evol 2, 323–328 (1973). https://doi.org/10.1007/BF01654100
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DOI: https://doi.org/10.1007/BF01654100