Summary
Recent experiments on the interaction of amino acids with homopolyribonucleic acids as measured by proton magnetic resonance spectroscopy and on the interactions of ribonucleoside 5′-monophosphates with immobilized amino acids give relative binding strengths that are not reconcilable with the present genetic code in any simple way.
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Crick, F. H. C.: J. molec. Biol.38, 367 (1968).
Fox, S., Lacey, J., Yubi, A.: Abstract, Joint Conference Chem. Inst. of Canada and Am. Chem. Soc., Toronto, May 1970.
Héléne, C.: Nature (Lond.) New Biol.234, 120 (1971).
Lacey, J. C., Pruitt, K. M.: Nature (Lond.)223, 799 (1969).
Leng, M., Felsenfeld, G.: Proc. nat. Acad. Sci. (Wash.)56, 1325 (1966).
Orgel, L. E.: J. molec. Biol.38, 381 (1968).
Raszka, M., Mandel, M.: Proc. nat. Acad. Sci. (Wash.)68, 1190 (1971).
Raszka, M., Mandel, M.: First European Biophysics Congress Baden, Sept. 1971.
Saxinger, W. C., Ponnamperuma, C.: J. molec. Evolution1, 63 (1971).
Woese, C. R.: The genetic code. New York: Harper and Row 1967.
Woese, C. R.: J. molec. Biol.43, 235 (1969).
Woese, C. R., Dugre, D. H., Saxinger, W. C., Dugre, S. A.: Proc. nat. Acad. Sci. (Wash.)55, 966 (1966).
Zubay, G., Doty, P.: Biochim. biophys. Acta (Amst.)29, 47 (1958).
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Raszka, M., Mandel, M. Is there a physical chemical basis for the present genetic code?. J Mol Evol 2, 38–43 (1972). https://doi.org/10.1007/BF01653941
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DOI: https://doi.org/10.1007/BF01653941