Summary
In the present study the relationship between plasma and whole blood taurine was examined under normal physiological circumstances in humans and cats. In addition, the effect of taurine supplementation on plasma and whole blood taurine was evaluated in humans and the depletion of taurine pools after a taurine-deprived diet was studied in cats. The normal plasma taurine concentration in humans was 44±8 µmol/L and the whole blood taurine concentration was 227±35 µmol/L. Under normal physiological conditions plasma and whole blood taurine were not correlated (r=0.092). Plasma taurine responded rapidly to dietary supplementation in humans or the taurine depletion in cats. In contrast, the whole blood taurine pool was more inert and varied only under extremes of depletion (cats) or sustained taurine supplementation.
Zusammenfassung
Die vorliegende Studie untersuchte die Beziehung zwischen der Taurinkonzentration in Plasma und Gesamtblut unter normalen physiologischen Bedingungen bei Menschen und bei Katzen sowie nach oraler Taurinsupplementierung beim Menschen und nach taurinfreier Fütterung bei Katzen. Beim Menschen betrug die durchschnittliche Taurinkonzentration im Plasma 44±8 µmol/L und im Gesamtblut 222±35 µmol/L. Unter diesen „physiologisch normalen“ Bedingungen bestand zwischen der Taurinkonzentration in Plasma und Gesamtblut keine Korrelation (r=0.092). Die Plasmataurinkonzentration stieg nach oraler Taurinsupplementierung beim Menschen rasch an bzw. fiel schnell nach taurinfreier Ernährung bei Katzen ab. Die Taurinkonzentration im Gesamtblut war dagegen mehr inert und änderte sich erst nach anhaltender Taurinzufuhr beim Menschen bzw. nach andauerndem Taurinmangel bei Katzen.
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Trautwein, E.A., Hayes, K.C. Plasma and whole blood taurine concentrations respond differently to taurine supplementation (humans) and depletion (cats). Z Ernährungswiss 34, 137–142 (1995). https://doi.org/10.1007/BF01636947
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DOI: https://doi.org/10.1007/BF01636947