Summary
The monohydrazones derived from the condensation of diacetyl and benzil with hydrazine-S-methylcarbodithioate (Dahydth) and (Benhydth) were prepared and their ligation properties with nickel(II), copper(II), palladium(II), zinc(II) and cadmium(II) were studied. A series of bisligand chelates were isolated and characterized. In the zinc(II), cadmium(II) copper(II) and palladium(II) bisligand chelates, both Dahydth and Benhydth act as mononegative bidentate molecules. The Ni(Dahydth-H)2 chelate possesses an octahedral structure where Dahydth acts as a mononegative tridentate ligand. The1H n.m.r. spectra of the two ligands as well as of the diamagnetic metal(II) chelates are discussed. The fragmentation in a mass spectrometer of all these chelates was also studied.
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References
F. A. Frensh and B. L. Freedlander,Cancer Research, 18, 1290 (1958).
H. G. Petering, H. H. Buskirk and G. F. Underwood,Cancer Research, 24, 367 (1964);31, 228 (1971).
E. Mihich and C. A. Nichol,Cancer Research, 25, 1410 (1965).
B. Booth and A. C. Satorelli,Nature, 210, 104 (1966).
J. Cappuccino, M. Arakawa and M. Balis,J. Med. Chem., 11, 339 (1968).
A. C. Sartorelli and W. A. Creasey,Ann. Rev. Pharmacol, 9, 51 (1969).
J. A. Crim and H. G. Petering,Cancer Research, 27, 1278 (1967).
G. Bahr,Z. Anorg. Allgem. Chem., 268, 351 (1952); 273, 325 (1953); 275, 136 (1955).
B. A. Gingras, T. Suprunchuk and C. H. Bayley,Can. J. Chem., 40, 1053 (1962).
M. R. Taylor, E. J. Gabe, J. P. Glusker, J. A. Minkin and A. L. Patterson,J. Am. Chem. Soc., 88, 1845 (1966).
C. J. Jones and J. A. McCleverty,J. Chem. Soc. A, 2829 (1970).
L. E. Warren, S. M. Horner and W. E. Hatfield,J. Am. Chem. Soc., 94, 6392 (1972).
D. H. Petering,Bioinorg. Chem., 1, 255 (1972);1, 273 (1972).
M. R. Taylor, J. P. Glusker, E. J. Gabe and J. A. Minkin,Bioinorg. Chem., 3, 189 (1974).
D. A. Winkelmann, Y. Bermke and D. H. Petering,Bioinorg. Chem., 3, 201 (1974).
M. J. M. Campbell, A. J. Collis and R. Grzeskowiak,J. Inorg. Nucl. Chem., 38, 173 (1976).
K. Balschmiter, H. Greber and H. G. Steinhauser,J. Inorg. Nucl. Chem., 40, 631 (1978).
G. W. Bushnell and A. Y. M. Tsang,Can. J. Chem., 57, 603 (1979).
M. Das and S. E. Livingstone,Inorg. Chim. Acta, 19, 5 (1976).
B. Chiswell,Inorg. Chim. Acta, 41, 165 (1980).
M. F. Iskander, L. El-Sayed and A. El-Toukhy,J. Inorg. Nucl. Chem., 42, 1145 (1980).
S. O. Ajayi and D. R. Goddard,J. Chem. Soc. A, 2673 (1971).
M. F. Iskander, M. M. Mishrikey, L. El-Sayed and A. El-Toukhy,J. Inorg. Nucl. Chem., 41, 815 (1979).
S. W. Schneller,Int. J. Sulphur Chem. Pt. B, 7, 295 (1972).
S. Kawanishi, A. Yokoyama and T. Tanaka,Chem. Pharm. Bull. Jpn., 20, 262 (1972).
A. R. Hendricks and R. L. Martin,Inorg. Chem., 14, 914 (1975).
B. M. Dahl and P. H. Nielsen,Acta Chem. Scand., B28, 1091 (1974).
M. F. Iskander, L. El-Sayed, A. El-Toukhy and M. Tawfik,Transition Met. Chem. (1981) in press.
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El-Toukhy, A., El-Essawi, M., Tawfik, M. et al. Coordination compounds of transition metal hydrazine derivatives. Part 25. Monohydrazine-S-methylcarbodithioate schiff bases derived from α-dicarbonyl compounds. Transition Met Chem 7, 158–163 (1982). https://doi.org/10.1007/BF01035832
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DOI: https://doi.org/10.1007/BF01035832