Summary
Streptomyces hygroscopicus mutants showing altered fermentation kinetics were isolated using a selection procedure in a chemostat. Several mutants were obtained which differed in their capacity to produce the macrolide antibiotic turimycin.
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Roth, M., Neigenfind, M., Bormann, E.J. et al. Use of chemostat for selection ofStreptomyces hygroscopicus mutants altered in regulation of maltose utilization. Biotechnol Lett 8, 479–484 (1986). https://doi.org/10.1007/BF01025205
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DOI: https://doi.org/10.1007/BF01025205