Summary
Non-limiting nutritional conditions revealed a growth-associated erythromycin production with ammonium sulfate while the relation was growth-dissociated for ammonium nitrate. Feeding experiments suggested that the residual nitrate level might be the key regulatory element. A nitrate-induced glutamine synthetase pathway was postulated according to the nature and initial concentration of the ammonium salt.
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Potvin, J., Péringer, P. Ammonium regulation inSaccharopolyspora erythraea. Part II: Regulatory effects under different nutritional conditions. Biotechnol Lett 16, 69–74 (1994). https://doi.org/10.1007/BF01022626
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DOI: https://doi.org/10.1007/BF01022626