Summary
The pathology of two cases of a canine myopathy associated with myotonia are presented. The changes were interpreted as dystrophic. The most obvious features were a rounding on cross section and variation in fibre size with numerous internal nuclei, many of which formed chains. Degeneration and regenaration were seen and there was a slight increase in perimysial and endomysial connective tissue. Only one ringed fibre was seen, but no sarcoplasmic masses. Enzyme histochemistry failed to demonstrate any selective Type I fibre atrophy. The peripheral and central nervous systems were normal in both cases.
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Duncan, I.D., Griffiths, I.R. & McQueen, A. A myopathy associated with myotonia in the dog. Acta Neuropathol 31, 297–303 (1975). https://doi.org/10.1007/BF00687924
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DOI: https://doi.org/10.1007/BF00687924