Summary
The histopathological findings in the optic nerves and chiasm in relation to atherosclerosis of the circle of Willis are reported. The material was derived from 101 autopsy cases, in which 58 showed various degrees of atherosclerosis, estimated by the method of Bakeret al. In 6 cases without atherosclerosis of the circle of Willis histopathological changes in the optic nerves were also found. Fibrous thickening of the leptomeninges, fibrous thickening of the walls of intraneural blood vessels and perivascular atrophy of neural tissue were observed most frequently.
Zusammenfassung
Es werden die histopathologischen Befunde in den Nervi optici und im Chiasma in bezug auf die Atherosclerose des Circulus Willisii berichtet. Das Material wurde von 101 Autopsiefällen gesammlt, von denen 58 Atherosclerose verschiedenen Grades nach Auswertung mit der Methode von Baker et al. zeigten. 6 Fälle ohne Atherosclerose zeigten in den Nervi optici ebenfalls Veränderungen. Fibröse Verdickung der Leptomeningen, sowie der intraneuralen Blutgefäße und perivasculäre Atrophie des neuralen Gewebes wurden am häufigsten beobachtet.
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References
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Routsonis, K.G. Histopathological changes in the intracranial portion of the optic nerves in cerebral atherosclerosis. Acta Neuropathol 16, 77–82 (1970). https://doi.org/10.1007/BF00686967
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DOI: https://doi.org/10.1007/BF00686967