Abstract
The synthesis of isoagatholactone has been effected by the successive oxidation of (14R)-isoagath-12-en-15-ol with selenium dioxide and manganese dioxide. Methyl spongia-13(16),14-dien-19-oate has been obtained by the cyclization of methyl lambertianate with 100% sulfuric or fluorosulfonic acid.
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Institute of Chemistry, Academy of Sciences of the Moldavian SSR, Kichinev. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 725–731, November–December, 1984.
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Vlad, P.F., Ungur, N.D. Cyclization and rearrangement of diterpenoids. III. Synthesis of isoagatholactone and methyl spongia-13(16),-14-dien-19-oate. Chem Nat Compd 20, 685–691 (1984). https://doi.org/10.1007/BF00580023
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DOI: https://doi.org/10.1007/BF00580023