Summary
Porous coralline and synthetic hydroxyapatite blocks reinforced with either self-reinforced polyactide or polyglycolide were implanted into 15 lumbar intervertebral disc spaces in five minipigs in order to determine whether they could provide an osteoconductive bridge for interbody fusion. Histological examination and radiological analysis with plain films, computed tomography and magnetic resonance imaging were carried out. The osteoconductive properties were promising; creeping bone formation could be observed, although no complete fusion had been achieved at 24 weeks.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Böstman O, Hirvensalo E, Vainionpää S, Mäkelä A, Vihtonen K, Törmälä P, Rokkanen P (1989) Ankle fractures treated using biodegradable internal fixation. Clin Orthop 238:195–203
Bucholz RW, Carlton A, Holmes R (1989) Interporous hydroxyapatite as a bone graft substitute in tibial plateau fractures. Clin Orthop 240:53–62
Cook SD, Reynolds MC, Whitecloud TS, Routman AS, Harding AF, Kay JF, Jarcho M (1986) Evaluation of hydroxylapatite graft materials in canine cervical spine fusions. Spine 11:305–309
Eggli PS, Miller W, Schenk RK (1988) Porous hydroxyapatite and tricalcium phosphate cylinders with two different pore size ranges implanted in the cancellous bone of rabbits. A comparative histomorphometric and histologic study on bony ingrowth and implant substitution. Clin Orthop 232:127–138
Goldner J (1938) A modification of Masson trichrome technique for routine laboratory purposes. Am J Pathol 14:237–243
Holmes RE, Bucholz RW, Mooney V (1981) Porous hydroxyapatite as a bone-graft substitute in metaphyseal defects. A histometric study. J Bone Joint Surg [Am] 68:904–911
Jarcho M (1981) Calcium phosphate ceramics as hard tissue prosthetics. Clin Orthop 157:259–278
Klein CP, Patka P, den Hollander W (1989) Macroporous calcium phosphate bioceramics in dog femora: a histological study of interface and biodegradation. Biomaterials 10(1):59–62
Modic MT, Steinberg PM, Ross JS, Masaryk TL, Carter JR (1988) Degenerative disk disease: assessment of changes in vertebral body marrow with MR imaging. Radiology 166:193–199
Nasca RJ, Lemons JE, Deinlein DA (1989) Synthetic biomaterials for spinal fusion. Orthopedics 12:543–548
Passuti N, Daculsi G, Rogez JM, Martin S, Bainvel JV (1989) Macroporous calcium phosphate ceramic performance in human spine fusion. Clin Orthop 248:169–176
Schneider JR, Bright RW (1976) Anterior cervical fusion using preserved bone allografts. Transplant Proc 8 [Suppl 1]:73–76
Senter HJ, Kortyna R, Kemp WR (1989) Anterior cervical discectomy with hydroxylapatite fusion. Neurosurgery 25:39–43
Shima T, Keller JT, Alvira MM, Mayfield FH, Dunsker SB (1979) Anterior cervical discectomy and interbody fusion. J Neurosurg 51:533–538
Taheri ZE, Gueramy M (1972) Experience with calf bone in cervical interbody spinal fusion. J Neurosurg 36:67–71
Tencer AF, Woodard PL, Swenson J (1988) Mechanical and bone ingrowth properties of a polymer-coated, porous, synthetic, coralline hydroxyapatite bone-graft material. Ann New York Acad Sci 523:157–172
Törmälä P, Taurio R, Pellinen M, Ylinen P, Vainionpää S (1989) Reinforcing of porous hydroxyapatite blocks with polylactide composite. Trans VII Internat Conference of Polymers in Medicine and Surgery 3:1–5
White AA, Southwick WO, DePonte RJ, Gainor JW, Hardy R (1973) Relief of pain by anterior cervical spine fusion for spondylosis: a report of sixty-five cases. J Bone Joint Surg [Am] 55:525–534
Ylinen P, Taurio R, Vainionpää S, Toivonen T, Törmälä P, Rokkanen P (1991) Evaluation of bone ingrowth into the or lactide fibres. Abstract. New trends in bone grafting, block of porous hydroxyapatite reinforced with glycolide Tempere, Finland, March 21–23
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ylinen, P., Kinnunen, J., Laasonen, E.M. et al. Lumbar spine interbody fusion with reinforced hydroxyapatite implants. Arch Orthop Trauma Surg 110, 250–256 (1991). https://doi.org/10.1007/BF00572882
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00572882