Abstract
• Background: Nasolacrimal occlusion has been shown to improve the efficacy of some topically applied ocular drugs. The aim of this study was to investigate the effect of nasolacrimal occlusion on tropicamide-induced mydriasis. • Methods: We compared pupillary dilatation by 0.125% tropicamide with and without nasolacrimal occlusion in 40 healthy volunteers. • Results: Analysis of variance with repeated measures failed to show any advantage due to nasolacrimal occlusion in drug-induced mydriasis.
• Conclusion: Nasolacrimal occlusion did not increase the mydriasis obtained with 0.125% tropicamide.
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Loewenstein, A., Sadeh, A., Goldstein, M. et al. The effect of nasolacrimal occlusion on drug-induced mydriasis. Graefe's Arch Clin Exp Ophthalmol 233, 530–531 (1995). https://doi.org/10.1007/BF00183435
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DOI: https://doi.org/10.1007/BF00183435