Abstract
We have sequenced the nucleotides of the regions that encode the capsid protein VP1 of the foot-and-mouth disease viruses (FMDV) A5Bernbeuren/1984 and A Iran/1987. Amino acid sequences and secondary protein structures are provided. Both proteins consist of 212 amino acids. The sequences and secondary structures are compared to those of FMDV A22/CCCP/64, a strain previously endemic in the Near East. Nucleotide divergency among the three sequences is highest for FMDV A5Bernbeuren/1984 (18% compared to 13% for each other case). Thirty amino acid divergencies are observed between A22/CCCP/64 and A5 Bernbeuren/1984 or A Iran/1987, whereas the latter two differ by 27 residues. The secondary structures of all three proteins are different. A Iran/1987 is considered to belong to a thus far unknown subtype.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Brooksby J.B., Intervirology 18:1–23, 1982.
Strohmaier K., Franze R. and Adam K.-H., J Gen Virol 59:295–306, 1982.
Kurz C., Forss S., Küpper H., Strohmaier K. and Schaller H., Nucl Acids Res 9: 1919–1931, 1981.
Makoff A.J., Paynter C.A., Rowlands D.J. and Boothroyd J.C., Nucl Acids Res 10: 8285–8295, 1982.
Boothroyd J.C., Harris T.J.R., Rowlands D.J. and Loeve P.A., Gene 17:153–161, 1982.
Cheung A., Delamarter J., Weiss S. and Küpper H., J Virol 48:451–459, 1983.
Beck E., Feil G. and Strohmaier K., EMBO J 2:555–559, 1983.
Villanueva N., Davila M., Ortin J. and Komingo E., Gene 23:185–194, 1983.
Weddell G.N., Yansura D.G., Dowbenko D.J., Hoaltin M.E., Grubman M.J., Moore D.M. and Kleid D.G., Proc Natl Acad Sci USA 82:2618–2622, 1985.
Sobrino F., Palma E.L., Beck E., Davila M., de laTorre J., Negro P., Villanueva N., Ortin J. and Domingo E., Gene 50:149–159, 1986.
Beck E. and Strohmaier K., J Virol 61:1621–1629, 1987.
Ahl R., Tierärztl Umschau 42:204–210, 1987.
Ahl R., Arch Gesamte Virusforsch 46:302–314, 1974.
Chomczynski R. and Sacci N., Anal Biochem 162:156–159, 1987.
Thomas P.S., Proc Natl Acad Sci USA 77:5201–5205, 1980.
Sanger F., Nicklen S. and Coulson A.R., Proc Natl Acad Sci USA 74:5463–5467, 1977.
Devereux J., Haeberli P. and Smithies O., Nucl Acids Res 12:387–395, 1983.
Samuel A.R., Knowles N.J. and Kitching R.P., Epidem Inf, in press.
Chou P.Y. and Fasman G.D., Adv Enzymol 47:45–147, 1978.
Becker Y., in: Foot and Mouth Disease 17th Conference, Paris 1986, Office Internat. des Epizooties, France, 1987, pp. 152–168.
Hogle J.M., Chow M. and Filman D.J., Science 229:1358–1365, 1985.
Luo M., Vriend G., Kamer G., Minor I., Arnold E., Rossmann M.G., Boege U., Scraba D.G., Duke G.M. and Palmenberg A.C., Science 235:182–193, 1987.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Marquardt, O., Adam, KH. Sequences of capsid protein VP1 of two type a foot-and-mouth disease viruses. VIRUS GENES 2, 283–291 (1989). https://doi.org/10.1007/BF00125344
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00125344