Abstract
A new approach to the study of the brain and its functions known as Human Connectomics has been recently established. Starting from magnetic resonance images (MRI) of brain scans, it is possible to identify the fibers that link brain areas and to build an adjacency matrix that connects these areas, thus creating the brain connectome. The topology of these networks provides a lot of information about the organizational structure of the brain (both structural and functional). Nevertheless this knowledge is rarely used to investigate the possible emerging brain dynamics linked to cognitive functions. In this work, we implement finite state models on neural networks to display the outcoming brain dynamics, using different types of networks, which correspond to diverse segmentation methods and brain atlases. From the simulations, we observe that the behavior of these systems is completely different from random and/or artificially generated networks. The emergence of stable structures, which might correspond to brain cognitive circuits, has also been detected.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
O. Sporns et al., Networks of the brain (MIT Press, Cambridge, MA, USA, 2011)
O. Sporns et al., Discovering the human connectome (MIT Press, Cambridge, MA, USA, 2012)
W. Singer et al., Neuron 24, 49 (1999)
A.R. Luria et al., Higher cortical functions in man (Basic Books, New York, NY, USA, 1966)
M.M. Mesulam et al., Brain 121, 1013 (1998)
D.R. Gitelman, A.C. Nobre, T.B. Parrish, K.S. LaBar, Y.H. Kim, J.R. Meyer, M.M. Mesulam, Brain 122, 1093 (1999)
S.L. Bressler, V. Menon, Trends Cognit. Sci. 14, 277 (2010)
G. Buzsaki et al., Rhythms of the brain (Oxford University Press, New York, NY, USA, 2006)
A.K. Engel, P.R. Roelfsema, P. Fries, M. Brecht, W. Singer, Cereb. Cortex 7, 70 (1997)
W.M. Freeman et al., Mass Action in the nervous system (Academic Press, New York, NY, USA, 1975)
M.A. Arbib, P. Erdi, J. Szentagothai, Neural organization: structure, function, and dynamics (MIT Press, Cambridge, MA, USA, 1998)
C. Koch, J.L. Davis, Large-scale neuronal theories of the brain (MIT Press, Cambridge, MA, USA, 1994)
S.L. Bressler, J.A. Kelso, Trends Cognit. Sci. 5, 26 (2001)
M.M. Mesulam et al., Ann. Neurol. 28, 597 (1990)
S.L. Bressler et al., Brain Res. Rev. 20, 288 (1995)
A.R. McIntosh et al., Neural Netw. 13, 861 (2000)
J.M. Fuster et al., Cortex and mind: unifying cognition (Oxford University Press, New York, NY, USA, 2003)
O. Sporns, D.R. Chialvo, M. Kaiser, C.C. Hilgetag, Trends Cognit. Sci. 8, 418 (2004)
C. Sauvage, N., De Greef, M. Manto, P. Jissendi, C. Nioche, C. Habas, J. Neuroradiol. 42, 115 (2015)
S. Eickhoff, T.E. Nichols, J.D. Van Horn, J.A. Turner, NeuroImage 124, 1065 (2016)
V. Volman, M. Perc, M. Bazhenov, PLoS One 6, e20572 (2011)
D. Fan, Q. Wang, M. Perc, Sci. Rep., 5, 12618 (2015)
B.K. Bera, S. Majhi, D. Ghosh, M. Perc, Europhys. Lett. 118, 10001 (2017)
J.F. Hipp, A.K. Engel, M. Siegel, Neuron 69, 387 (2011)
G. Deco, V.K. Jirsa, P.A. Robinson, M. Breakspear, K. Friston, PLoS Comput. Biol. 4, e1000092 (2008)
S.A. Kauffman et al., J. Theor. Biol. 22, 437 (1969)
B. Drossel et al., in Annual review of nonlinear dynamics and complexity (Wiley, New York, NY, USA, 2008), Vol. 1
D., Cheng, H. Qi, IEEE Trans. Neural. Netw. Learn. Syst. 21, 584 (2010)
E. Bilotta, P. Pantano, S. Vena, Int. J. Bifurc. Chaos 21, 373 (2011)
E. Bilotta, P. Pantano, Int. J. Bifurc. Chaos 21, 1501 (2011)
Q. Wei, C.J. Xie, Y. Liang, Y.J. Niu, D. Lin, AIP Adv. 6, 015013 (2016)
O. Sporns, G. Tononi, R. Kötter, PLoS Comput. Biol. 1, 0245 (2005)
T.E. Behrens, O. Sporns, Curr. Opin. Neurobiol. 22, 144 (2012)
A. Fornito, E.T. Bullmore, Eur. Neuropsychopharmacol. 25, 733 (2015)
M. Rubinov, O. Sporns, Neuroimage 52, 1059 (2009)
M. Gardner et al., Sci. Am. 223, 120 (1970)
E. Bilotta, F. Stranges, P. Pantano, Int. J. Bifurc. Chaos 17, 657 (2007)
E. Bilotta, P. Pantano, A gallery of Chua attractors (World Scientific, Singapore, 2008)
E. Tognoli, J.S. Kelso, Neuron 81, 35 (2014)
G. Deco, M.L. Kringelbach, Trends Neurosci. 39, 125 (2016)
C.G. Langton et al., Physica D 42, 12 (1990)
F. Bertacchini, E. Bilotta, P. Pantano, Comput. Hum. Behav. 77, 382 (2017)
M. Abdechiri, K. Faez, H. Amindavar, E. Bilotta, Nonlinear Dyn. 87, 2597 (2017)
E. Bilotta, P. Pantano, S. Vena, IEEE Trans. Neural. Netw. Learn. Syst. 28, 1228 (2017)
M.C. Lombardo, R. Barresi, E. Bilotta, F. Gargano, P. Pantano, M. Sammartino, J. Math.Biol. 75, 373 (2017)
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Bertacchini, F., Bilotta, E., Lombardo, M.C. et al. Brain-like large scale cognitive networks and dynamics. Eur. Phys. J. Spec. Top. 227, 787–797 (2018). https://doi.org/10.1140/epjst/e2018-800021-6
Received:
Revised:
Published:
Issue Date:
DOI: https://doi.org/10.1140/epjst/e2018-800021-6