Abstract
The level of gene expression and the protein content of tyrosine hydroxylase and dopamine β-hydroxylase were determined. In the perinatal period of rats, when noradrenaline functions as a morphogenetic factor, the level of gene expression of these enzymes increased and the content of protein products of these genes was almost unchanged, indicating the difference in the regulatory mechanisms of their transcription and translation.
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Nomura, Y., Naitoh, F., and Segawa, T., Brain Res., 1976, vol. 101, pp. 305–315.
Huber, K., Kalcheim, C., and Unsicker, K., Auton. Neurosci., 2009, vol. 151, pp. 10–16.
Verhofstad, A.A.J., Hokfelt, T., Goldstein, M., Steinbusch, H.W.M., and Joosten, H.W.J., Cell Tissue Res., 1979, vol. 200, pp. 1–13.
Kozina, E.A., Khakimova, G.R., and Khaindrava, V.G., J. Neurol. Sci., 2014, vol. 340, pp. 198–207.
Bookout, A.L., Cummins, C.L., Mangelsdorf, D.J., Pesola, J.M., and Kramer, M.F., Curr. Protoc. Mol. Biol., 2006, pp. 15.8.1–15.8.28.
Laemmli, U.K., Nature, 1970, vol. 227, pp. 680–685.
Levitt, M., Spector, S., Sjoerdsma, A., and Udenfriend, S., J. Pharm. Exp. Ther., 1965, vol. 148, pp. 1–8.
Nakashima, A., J. Neurochem., 2012, vol. 120, pp. 199–201.
Tischler, A.S. and DeLellis, R.A., Int. J. Toxicol., 1988, vol. 7, pp. 1–21.
Ciaranello, R.D., Wooten, G.F., and Axelrod, J., J. Biol. Chem., 1975, vol. 250, pp. 3204–3211.
Tishler, A., Toxicol. Pathol., 1989, vol. 17, pp. 330–332.
Verhofstad, A.A.J., Coupland, R.E., Parker, T.R., and Goldstein, M., Cell Tissue Res., 1985, vol. 242, pp. 233–243.
Tomlinson, A., Durbin, J., and Coupland, R.E., Neuroscience, 1987, vol. 20, pp. 895–904.
Murtazina, A., Nikishina, Yu., Bondarenko, N., Sapronova, A., and Ugrumov, M., Dokl. Biochem. Biophys., 2016, vol. 466, pp. 74–76.
Kvetňanský, R., Jahnova, E., Torda, T., Štrbák, V., Baláž, V., and Macho, L., Mech. Ageing Dev., 1978, vol. 7, pp. 209–216.
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Original Russian Text © N.S. Bondarenko, A.R. Murtazina, Yu.O. Nikishina, A.Ya. Sapronova, M.V. Ugrumov, 2017, published in Doklady Akademii Nauk, 2017, Vol. 472, No. 3, pp. 341–344.
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Bondarenko, N.S., Murtazina, A.R., Nikishina, Y.O. et al. Molecular mechanisms of synthesis of noradrenaline as an inducer of development in the adrenal glands of rats in ontogenesis. Dokl Biochem Biophys 472, 23–26 (2017). https://doi.org/10.1134/S1607672917010070
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DOI: https://doi.org/10.1134/S1607672917010070