Abstract
5,5,7-Trimethyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ol was synthesized by cyclocondensation of 3-amino-1,2,4-triazole with 4-methylpent-3-en-2-one; its chemical transformations, and also the transformations of 5-phenyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ol were investigated in reactions with reagents of diverse electronic nature.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Chebanov, V.A. and Desenko, S.M., Curr. Org. Chem., 2006, vol. 10, p.297.
Lipson, V.V. and Gorobets, N.Yu., Mol. Div., 2009, vol. 13, p.399.
Bariwal, J., Trivedi, J.C., and Van der Eycken, E.V., Top. Heterocycl. Chem., 2010, vol. 25, p.169.
Lipson, V.V., Karnozhitskaya, T.M., Shishkina, S.V., Shishkin, O.V., and Turov, A.V., Russ. Chem. Bull., 2009, vol. 58, p. 1441. doi 10.1007/s11172-009-0193-1
Lipson, V.V., Karnozhitskaya, T.M., Shishkina, S.V., Shishkin, O.V., and Turov, A.V., Russ. J. Org. Chem., 2008, vol. 44, p. 1695. doi 10.1134/S1070428008110225
Zefirov, N.S., Palyulin, V.A., and Dashevskaya, E.E., J. Phys. Org. Chem., 1990, vol. 3, p.147.
Desenko, S.M., Orlov, V.D., Lipson, V.V., Shishkin, O.V., Lindeman, S.V., and Struchkov, Yu.T., Chem. Heterocycl. Compd., 1991, vol. 27, p. 1242. doi 10.1007/BF00471754
Sheldrick, G.M., Acta Cryst., Sect. A, 2008, vol. 64, p. 112.
Author information
Authors and Affiliations
Corresponding author
Additional information
Original Russian Text © N.I. Zemlyanaya, T.M. Karnozhitskaya, V.I. Musatov, I.S. Konovalova, S.V. Shishkina, V.V. Lipson, 2018, published in Zhurnal Organicheskoi Khimii, 2018, Vol. 54, No. 8, pp. 1227–1235.
Rights and permissions
About this article
Cite this article
Zemlyanaya, N.I., Karnozhitskaya, T.M., Musatov, V.I. et al. Synthesis and Chemical Transformations of 5-Alkyl(phenyl)-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-oles. Russ J Org Chem 54, 1241–1249 (2018). https://doi.org/10.1134/S1070428018080201
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S1070428018080201