Abstract
Depending on the reactant structure, reactions of substituted 3-(2-phenylpyrimidin-5-yl)propanoic acids with 2-aminopyridine, p-toluidine, and 2-aminophenol in polyphosphoric acid afforded the corresponding N-(pyridin-2-yl)propanamides, 5-[2-(benzoxazol-2-yl)ethyl]pyrimidine, and pyrido[2,3-d]pyrimidinones.
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Original Russian Text © A.A. Harutyunyan, H.A. Panosyan, S.G. Chishmarityan, R.A. Tamazyan, A.G. Ayvazyan, 2015, published in Zhurnal Organicheskoi Khimii, 2015, Vol. 51, No. 3, pp. 373–376.
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Harutyunyan, A.A., Panosyan, H.A., Chishmarityan, S.G. et al. One-step synthesis of pyrido[2,3-d]pyrimidines, amides, and benzoxazolylethylpyrimidine by condensation of substituted 3-(2-phenylpyrimidin-5-yl)propanoic acids with aromatic amines in polyphosphoric acid. Russ J Org Chem 51, 357–360 (2015). https://doi.org/10.1134/S1070428015030112
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DOI: https://doi.org/10.1134/S1070428015030112