Abstract
Novel polycyclic compounds, 1-pyrene-based pyridone derivatives, are synthesized by treatment of pyrenyl acetohydtazide with several arylidenemalononitriles and acetylacetone. Intramolecular cyclization furnishes the functionalized substituted pyridine-2-ones with high yields. Structures of the products are elucidated from the spectral data. Tests on antibacterial activity of the products reveal their high antibacterial effect.
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Khalifa, N.M., Haiba, M.E., Taha, M.M. et al. Synthesis and Antibacterial Assay of Some New Pyrenyl Pyridine Candidates. Russ J Gen Chem 89, 319–323 (2019). https://doi.org/10.1134/S1070363219020245
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DOI: https://doi.org/10.1134/S1070363219020245