Abstract
A general approach towards synthesis of 2(5)-hydroxyalkyl-substituted 1,3-thiazole derivatives has been proposed. The method includes lithiation of 1,3-thiazole ring followed by reacting the formed thiazole lithium derivatives with electrophiles.
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Original Russian Text © V.O. Sinenko, S.R. Slivchuk, Ya.G. Bal’on, V.S. Brovarets, 2015, published in Zhurnal Obshchei Khimii, 2015, Vol. 85, No. 8, pp. 1298–1304.
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Sinenko, V.O., Slivchuk, S.R., Bal’on, Y.G. et al. Synthesis of 2,5-di(hydroxyalkyl)-1,3-thiazoles. Russ J Gen Chem 85, 1855–1861 (2015). https://doi.org/10.1134/S1070363215080113
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DOI: https://doi.org/10.1134/S1070363215080113