Abstract
A series of linear tetrapeptides and macrocyclic pentapeptides has been synthesized starting with N,N-bis(1-carboxy-2-substituted)-3,5-diaminocarbonyl)pyridine and N,N-bis(1-hydrazonyl-2-substituted)-3,5-diaminocarbonyl)pyridine. Structures of newly synthesized compounds were elucidated by IR, 1H and 13C NMR, and MS spectral data and elemental analysis.
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Amr, A.EG.E., El-Salam, O.I.A. & Al-Omar, M.A. Synthesis of chiral macrocycles: I. Synthesis and study of cyclo (N α-dinicotinoyl)pentapeptide candidates. Russ J Gen Chem 85, 1161–1166 (2015). https://doi.org/10.1134/S1070363215050278
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DOI: https://doi.org/10.1134/S1070363215050278