Abstract
A ruthenium complex modified with (1S,2S)-1,2-diphenyl-1,2-ethanediamine efficiently catalyzes asymmetric hydrogenation of 3-chloro-1-phenylpropan-1-one in the presence of potassium hydroxide solution in isopropyl alcohol, specific optical rotation of the synthesized products reaching −24.6°. Effects of the reaction time, hydrogen pressure, and the alkali concentration on the reaction course have been elucidated.
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Liu, Y., Tai, Y., Guan, R. et al. Asymmetric hydrogenation of 3-chloro-1-phenylpropan-1-one catalyzed by ruthenium complexes. Russ J Gen Chem 85, 922–925 (2015). https://doi.org/10.1134/S1070363215040271
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DOI: https://doi.org/10.1134/S1070363215040271