Abstract
The latencies and amplitudes of the P100 and N170 components of event related potentials (ERPs) upon presentation of neutral and threatening visual stimuli have been studied in healthy persons and patients with schizophrenia. The studied patients had acute psychosis with a predominance of hallucinatory-paranoid syndrome and did not receive antipsychotic therapy, i.e. when the disturbances of sensory perception were mostly pronounced. Analysis of early component P100 and intermediate one N170 of event relative potentials (ERPs) in the control group healthy showed the increase of excitation to emotionally threatening stimuli; at all sites the amplitude increased and the latency shortened. In the group of patients with schizophrenia, the analysis of components P100 and N170, in contrast, showed the increased latency and decreased amplitude. The obtained data point to pathological inhibition underlying the ERPs to emotionally significant stimuli.
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Original Russian Text © A.Y. Arkhipov, V.B. Strelets, 2015, published in Fiziologiya Cheloveka, 2015, Vol. 41, No. 4, pp. 31–36.
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Arkhipov, A.Y., Strelets, V.B. Neurophysiological features of perception to emotional stimuli in norm and patients with paranoid. Hum Physiol 41, 367–371 (2015). https://doi.org/10.1134/S0362119715040027
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DOI: https://doi.org/10.1134/S0362119715040027