Abstract
Objective
PM10 is one of the typical pollutants involved with sandstorm. More and more attentions on the sensitive bio-marks by PM10 exposure are attracted. This study is to probe the sensitivities indicators’ levels by sandstorm PM10 exposure.
Methods
A cross-sectional study involving administration on a survey 150 residents in Erlianhaote was performed. PM10 concentrations collected on a daily basis from the local monitor stations from March to June, 2016 were employed as the daily environmental exposure levels (DEEL). Indicators of IGM, CRP, CC16, IL16, IGA, LGG, IGE and IL8 were assayed, as well as questionnaire for individual disease histories were done.
Results
Results indicated that PM10 exposure level was positively related to IGG, IGM, IGA, LGG and CRP, age was positively related to CRP and LGG, and history of cardiovascular disease was related to CRP by multi-factor line regression analysis. Further analysis revealed that levels of IGG (p<0.01) and IGM (p<0.05) increased in the group with PM10 DEEL exceeded 200 μg/m3, compared to the group with the average exposure levels less than 200 μg/m3; while levels of IGM (p<0.05), IGA (p<0.05), LGG (p<0.05) and CRP (p<0.01) were found higher in the group with PM10 DEEL exceed 300 μg/m3, compare to the group with the levels less than 300 μg/m3.
Conclusion
Our findings suggest that sandstorm PM10 exposure might contribute to the changes of some immune and inflammation index. These findings provide clinical indicators for the sandstorm PM10 exposure and help to understand the risk of sandstorm pollution.
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Lv, S., Wang, H., Wang, B. et al. Study on the Sensitivity Indicators by Sandstorm PM10 Exposure. Toxicol. Environ. Health Sci. 10, 65–71 (2018). https://doi.org/10.1007/s13530-018-0348-2
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DOI: https://doi.org/10.1007/s13530-018-0348-2