Abstract
Objectives
We studied the profile of bloodstream infections (BSI) in the pediatric intensive care unit (PICU) and identified predictors of mortality.
Methods
The study collected data from hospital records for children younger than 18-years who developed BSI during their PICU stay between 2014 and 2019.
Results
In 114 patients, 136 PICU-acquired BSIs with 152 pathogens were documented. The incidence of BSI was 47.12/1000 PICU admissions and 7.95/1000 PICU hospital days. Gram-negative rods accounted for 75% of isolates, Gram-positive cocci accounted for 21.7% of isolates, and fungi accounted for 3.3% of isolated pathogens. ICU mortality was observed in 25 (21.9%) patients with a BSI compared to 94 (3.1%) patients without a BSI (P<0.001). Hemodynamic instability (P=0.014, OR 4.10, 95%CI 1.33–12.66), higher blood urea nitrogen (BUN) (P=0.044), and lower albumin levels (P=0.029) were associated with increased risk of ICU mortality.
Conclusion
BSI in the PICU is associated with increased mortality. Early identification and management of risk factors independently associated with poor clinical outcomes in these patients should be aimed to ensure improved survival.
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HDY,IK,KH: designed the study, analyzed the data and edited the manuscript; MA,RDS: gathered the data and reviewed the manuscript; JBA,AH, YSM,TA: helped in gathering the data and revising the manuscript. All authors approved the final version of manuscript, and are accountable for all aspects related to the study.
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Local Ethics Committee; No.0053-19-RMB, dated Jan 24, 2019.
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Additional material related to this study is available with the online version at www.indianpediatrics.net
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Dabaja-Younis, H., Alaiyan, M., Shalabi, R.D. et al. Six-Year Surveillance of Acquired Bloodstream Infection in a Pediatric Intensive Care Unit in Israel. Indian Pediatr 60, 41–44 (2023). https://doi.org/10.1007/s13312-023-2693-8
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DOI: https://doi.org/10.1007/s13312-023-2693-8