Abstract
Primary mammalian hepatocytes are used for several in vitro applications like drug metabolism and toxicity assays. The influence of substances on uptake and efflux transporters has to be evaluated during development as well. Therefore, we characterized the uptake and the efflux transport of different substrates in appropriate hepatocytes of different species.
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Keiser, M., Jia, J., Siegmund, W. et al. Methoden zur Transportercharakterisierung in primären Hepatozyten. Biospektrum 21, 188–190 (2015). https://doi.org/10.1007/s12268-015-0559-x
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DOI: https://doi.org/10.1007/s12268-015-0559-x