Introduction

Acetabular dysplasia is a well-recognized cause of hip pain and dysfunction with an associated risk of developing osteoarthritis (OA) [4, 9, 13, 19]. In this condition, insufficient coverage of the femoral head by the acetabulum leads to excessive joint contact pressures and subsequent accelerated joint degeneration. Quantification of femoral head coverage is historically based on the lateral center-edge angle (LCEA), described by Wiberg in 1939 [55]. The magnitude of the LCEA has been linked to the progression of OA even in the absence of symptoms during early adulthood [39], with one study noting a 13% increased likelihood of developing OA for each 1° loss of lateral coverage below 28° [49].

Reorientation of the acetabulum is the standard treatment of symptomatic acetabular dysplasia, as it permits repositioning of the available weight-bearing cartilage into a functional position. The periacetabular osteotomy (PAO), first described by Ganz, has become the standard treatment of symptomatic acetabular dysplasia as it permits acetabular reorientation to optimize acetabular coverage while maintaining posterior column integrity [22]. Numerous studies have characterized the success of PAO in the treatment of acetabular dysplasia, typically in cases with a preoperative LCEA < 17°, at both intermediate and long-term follow-up [22, 32, 48, 52].

Incomplete characterization of the pathology of borderline hip dysplasia continues to cloud treatment strategies. While the LCEA is a commonly used measurement modality in classifying hip dysplasia, it can mischaracterize or underdiagnose the nature of certain forms of acetabular undercoverage or other underlying hip pathology. A number of other radiographic measurements have been described in the assessment of hip dysplasia. Additionally, cross-sectional imaging has become a useful adjunct in preoperative planning. The purpose of this review is to discuss the current status of diagnosis and treatment options for borderline hip dysplasia.

Borderline Dysplasia

What Is “Borderline” Dysplasia?

According to Wiberg’s original description, hips with LCEA below 20° were considered pathologic and hips with LCEA over than 25° were normal. Hips with LCEA between 20 and 25o were considered uncertain. This uncertainty has created confusion in the literature concerning the spectrum of acetabular dysplasia severity, and nonspecific terms such as mild dysplasia [21, 29, 33, 37, 44, 53] and borderline dysplasia [5, 6, 11, 12, 14, 15, 20, 24, 27, 40] have been interchangeably used to describe these hips. The majority of currently available literature on these hips come from hip arthroscopy studies, and the definitions of “mild” and “borderline” coverage have varied from as low as 16° to as high as 28° (Table 1). Only a select few studies considered other radiographic parameters, such as the Tonnis angle, Sharp angle, or anterior center edge angle (ACEA) [27, 30].

Table 1 Classification of borderline acetabular dysplasia in orthopedic literature. LCEA, lateral center edge angle; ACEA, anterior center edge angle

How Do We Treat Borderline Dysplasia?

While acetabular reorientation with PAO is the generally accepted treatment for “traditional” hip dysplasia (LCEA < 17), the ideal treatment of borderline dysplasia remains controversial. Surgical treatment of borderline dysplasia has been advocated both through addressing the bony (PAO) or intra-articular (hip arthroscopy) components of the pathology. Proponents of PAO tout its ability to address the structural deformity which gives rise to the associated soft tissue issues (labral tears, capsular attenuation, etc.), at the expense of a greater surgical exposure with a prolonged recovery and higher potential complications. Proponents of hip arthroscopy to address the effected capsular and intra-articular structures (labral repair, cam-type femoral deformity resection, capsular repair, and/or plication) tout the minimally invasive approach and its expedited recovery at the expense of leaving the acetabular bony pathology unchanged.

Arthroscopic interventions to address the soft tissue pathology of borderline acetabular dysplasia have been described with variable success [4, 6, 15, 21, 26, 27, 30, 33, 40]. Several studies have shown good functional results of hip arthroscopy for the treatment of intra-articular pathology in patients with borderline dysplasia at short-term follow-up [6, 15, 26, 27, 40], while other studies noted inferior results of arthroscopy in patients with dysplasia [27, 30, 33]. A systematic review of hip arthroscopy in dysplastic patients noted a 14.1% revision rate and 9.5% rate of progression to total hip arthroplasty at an average of 29 months following hip arthroscopy [57••]. Two studies to date have focused specifically on outcomes of PAO in patients with LCEA between 18 and 25°, with improved patient reported outcomes and minimal complications at 1 year and 2 years postoperatively [34••, 46]. In the ANCHOR cohort, patients with “mild” dysplasia (LCEA > 15) did well following PAO but their improvements were not as significant as patients with more severe preoperative dysplasia [8].

Why Are We Failing?

The results of surgical outcomes for borderline dysplasia are variable at best. The unpredictability of results, especially with hip arthroscopy, may be attributable to a highly variable degree of acetabular morphology in patients with LCEA 18–25° when considering all radiographic measures of acetabular coverage. The LCEA is a reliable measure of lateral acetabular coverage, but is not a surrogate for the global morphology of the acetabulum. Other features of interest in these borderline hips include the anterior and posterior acetabular coverage, proximal femoral morphology, and rotational alignment of the proximal femur and acetabulum. All of these features should be evaluated and considered during the diagnostic evaluation of the symptomatic hip with borderline dysplasia, and better understanding of the global morphology of the hip may improve our surgical decision-making.

Imaging Evaluation of Borderline Dysplasia

Thorough imaging of non-arthritic hip disorders such as femoroacetabular impingement (FAI) and acetabular dysplasia are essential to develop appropriate treatment plans for these patients. The routine imaging evaluation typically begins with plain radiographs to develop an overall understanding of femoral and acetabular morphology. Ancillary imaging, such as CT and MRI are also frequently employed in these patients preoperatively to improve our understanding of the bony and soft tissue anatomy, respectively. With the increased utilization of ultrasound imaging for musculoskeletal pathology, its use will also likely expand in the diagnostic evaluation of hip pain. In the following sections, we will discuss each of these imaging modalities and note relevant measurements to aid in the evaluation of the borderline dysplastic hip.

Radiographs

Plain radiographs remain the standard first-line imaging modality for the majority of non-arthritic hip disorders. Clohisy et al. have provided a comprehensive review of non-arthritic hip radiography, providing practical details on the acquiring and interpretation of hip radiographs [7]. The typical radiographic sequence obtained in these individuals includes an AP pelvis (with attention to proper positioning and alignment), 45o Dunn-lateral, and false profile views. With this group of radiographs, it is possible to thoroughly evaluate much of the proximal femoral and acetabular morphology. The characterization of hip pathology using radiographic measures continues to be an evolving field. Several measurements utilized are the femoral neck-shaft angle (FNSA) [3], alpha angle [1], lateral center edge angle (LCEA) [55], anterior/ventral center edge angle (ACEA), Tonnis roof angle [50], anterior wall index (AWI) and posterior wall index (PWI) [47], and the femoral-epiphyseal acetabular roof (FEAR) index [56]. The relevant radiographic features to review will be discussed in this section, and pictorial descriptions can be found in Fig. 1.

Fig. 1
figure 1

Radiographic features of the proximal femur and acetabulum relevant to the diagnostic evaluation of borderline dysplasia. a Lateral center-edge angle (LCEA): angle formed between a perpendicular line (white line) to the line that connects the center of the femoral heads (white dashed lines) and a line (black line) that connects the center of the femoral head to the most lateral point of the acetabular sourcil. b Tönnis angle: angle formed between a line (black line) drawn between the most lateral and most medial points of the acetabular sourcil and a parallel line (white line) to the line (white dashed line) connecting the center of the femoral heads. c Anterior wall index (AWI) and posterior wall index (PWI): the femoral neck axis (white dashed line) is drawn from the midpoint of the neck to the center of the femoral head. The radius (r) of the femoral head is drawn (dashed white arrow) in line with the axis of the femoral neck. The point at which the axis of the femoral neck passes through the anterior wall and the point at which the axis of the femoral neck passes through the posterior wall are marked. The AWI is calculated by dividing distance “a” (black arrow) by the radius of the femoral head. The PWI is calculated by dividing distance “p” (white arrow) by the radius of the femoral head. d Posterior to anterior wall (P/A) index: the most lateral aspect of the acetabulum and the most inferior point of the tear drop point are connected by a line (solid white line), and a perpendicular line (white dashed line) is drawn at its midpoint. The acetabular articular surface is marked (white dashed circle). The distances from the anterior (black arrow) and posterior (white arrow) walls to the acetabular articular surface are measured, and the P/A index is calculated as p/a. e Anterior center-edge angle (ACEA): in the false profile radiograph, the center of the femoral head is marked, and a longitudinal line (white line) passing through the center of the femoral head is drawn. The ACEA is the angle formed by this line and a line connecting the center of the femoral head to the most anterior point of the acetabular sourcil (black line). f Alpha angle: the femoral neck axis is drawn by connecting the center of the femoral neck to the center of the femoral head (solid white line). A perfect circle is drawn around the femoral head, and the radius of the femoral head is measured (dashed white line, distance “r”). The point at which the distance from the center of the head exceeds the radius of the femoral head is marked. The alpha angle is the angle formed by a line connecting the center of the femoral head to the point at which the distance from the center of the head exceeds the radius of the femoral head (black line) and the femoral neck axis (white line). g Femoral neck-shaft angle: angle formed between the axis of the femoral neck (black line) and the longitudinal axis of the femoral shaft (white line). The width of the femoral neck (black dashed line) and the width of the femoral shaft (white dashed line) are drawn. h Femoral epiphyseal acetabular roof (FEAR) index: angle formed between a line (black line) representing the physeal scar of the femoral head and a line connecting the most medial and lateral points of the acetabular sourcil (white line). (Reprinted with permissions [35])

LCEA

The lateral center edge angle (LCEA) is a radiographic assessment of lateral acetabular coverage in the frontal plane using an AP pelvis radiograph. Multiple methods of performing the measurement have been described. First described by Wiberg et al., the measurement is formed by a vertical line (or parallel to long axis of the body) starting from the center of the femoral head with a line to the most lateral point of the acetabular roof [55]. A LCEA value of greater than 20° (patients age 3–17) or 25° (adults) is considered “normal.” Values less than 15° (patients age 3–17) or 20° (adults) are considered pathologic [18]. Hips with LCEA between these value ranges (15–20° in children and adolescents and 20–25° in adults) are considered “intermediate” or “uncertain” and treatment strategies are controversial.

Tonnis Angle

The Tonnis angle, or the “acetabular roof angle of Tonnis” or the “acetabular index” attempts to quantify the acetabular sourcil, or the weight-bearing portion of the acetabular roof [50]. The measurement is performed using an AP pelvis radiograph and is formed between a horizontal line and a tangential line extending from the medial edge to the lateral edge of the sourcil. Values greater than 13° are considered abnormal. The medial edge of the sourcil can be difficult to distinguish in some patients. The modified Tonnis angle was described as an alternative method in cases where the medial edge was unclear; in this method, the vertex of the femoral head was used as the site of a parallel line to the horizontal plane [16]. The point at which this line contacted the acetabulum was used as the medial edge for the tangential line towards the lateral point of the sourcil. The Tonnis angle and modified Tonnis angles have been observed to have a high degree of correlation in cases without joint space narrowing and subluxation of the hip.

AWI/PWI

The anterior wall index (AWI) and posterior wall index (PWI) attempt to characterize acetabular pathomorphology by quantifying the anterior and posterior acetabular coverage [47]. The measurement is performed using AP pelvis radiographs; the first step is to make a best fitting circle around the femoral head. A line is then drawn down the center of the femoral neck intersecting the center of the circle for the femoral head. The distance along this line was recorded from the edge of the circle measuring to the femoral head to the edge of the anterior wall (A) or the posterior wall (P). The AWI and PWI is calculated by dividing the measurement of the anterior wall coverage (A) or posterior wall coverage (P) by the radius of the femoral head circle. The average AWI for a normal hip was 0.41 with 0.28 for dysplastic hips and 0.61 for deep acetabuli. The average PWI for a normal hip was 0.91 with 0.81 for dysplastic hips and 1.15 for deep acetabuli.

ACEA

The anterior/ventral center edge angle (ACEA) utilizes the false-profile radiograph to evaluate the anterior acetabular coverage of the femoral head. The angle is measured by a vertical line through the center of the femoral head and a second line through the center of the hip towards the most anterior aspect of the acetabular dome [31]. Values less than 20° are considered abnormal [10].

FNSA

The femoral neck-shaft angle (FNSA), first described by Muller [38], is performed to quantify the degree of coxa vara or coxa valga. It is performed by measuring the angle between the mid-point of the femoral neck and the long axis of the femoral shaft. Variability exists in the method of performing the FNSA; one recent study comparing methods of measurement reported the best results with forming the femoral neck line from the center of a best fit circle around the femoral head. Femoral version should be considered in performing this measurement, as rotational changes can change the apparent FNSA on AP pelvis radiographs [28].

Alpha Angle

A common measurement used to assess for cam deformity is the alpha angle [43]. The alpha angle attempts to quantify the degree at which the femoral head transitions from being spherical. It is measured from the AP pelvis and Dunn lateral radiographs by first drawing a best fitting circle around the femoral head. Using the marker from the center of the femoral head, one line is drawn through the center of the femoral neck. A second neck is drawn to the point at which the femoral head loses its sphericity. The angle created by these two lines is the alpha angle. The thresholds for diagnosing cam have been debated, with values ranging from 50 to 83° indicating moderate to severe cam [1].

FEAR Index

The femoral-epiphyseal acetabular roof (FEAR) index was developed to assess for pathologic behavior in borderline dysplastic hips [56]. Using standard AP pelvic radiographs, the central third portion of the physeal scar of the femoral head is identified, and the most medial and lateral points of the straight section are used to create a line. The second portion of the angle is defined by the most medial and lateral points of the acetabular sourcil. The FEAR index can be either positive (angle facing laterally with apex medially) or negative (angle facing medially with apex laterally). The initial investigation of this measurement reported that painful hips with a LCEA under 25° and FEAR index less than 5° are likely to be stable, supporting a diagnosis of FAI rather than instability.

Cross Sectional Imaging

Obtaining information regarding anterior and posterior acetabular coverage, proximal femoral morphology, and rotational alignment of the femur and acetabulum is crucial in decision-making before potential surgical intervention in borderline hips. Three-dimensional (3D) imaging is a useful adjunct in the assessment and management of borderline hips. As the hip joint is a complex 3D structure, CT and MRI are able to provide additional details about specific anatomy and global morphology.

Ct

CT imaging is increasingly performed in the preoperative setting to characterize bony anatomy. The characterization of acetabular coverage in normal asymptomatic patients has been described, and several authors have previously characterized acetabular dysplasia on CT. Nepple et al. described a method of utilizing CT for determining variability in 3D acetabular deficiency and morphology [42••]. Also, by including cuts of the distal femur, CT enables precise calculation of both acetabular and femoral version [58]. Acetabular and femoral versions, and their combined relationship, impact the overall function of the hip and can predispose to either instability or impingement [17, 36]. Recent advancements have allowed for high quality CT imaging with much lower radiation exposure than previous testing [41].

MRI

MRI is the most commonly utilized non-invasive test for assessment of soft tissue structures in the assessment of the non-arthritic hip. In planning for surgical intervention, MRI can determine the presence of ligamentous, capsular, labral, tendinous, or osteochondral pathology. Alternative causes of hip pain, such as femoral neck stress fracture, avascular necrosis, or pigmented villonodular synovitis are also best evaluated with MRI. MRI arthrogram has been reported to have the best correlative results with arthroscopy, with labral tears having 92% sensitivity and 100% specificity [51]. However, one recent study suggested that non-arthrogramic hip MRI was a successful screening test for presence of labral tears, chondral defects, and ligamentum teres tears or synovitis [2]. In addition to providing details regarding intracapsular soft tissues, MRI also allows visualization of pericapsular structures. A small muscle overlying the anterior hip capsule called the iliocapsularis has been postulated as a secondary stabilizer of the hip capsule [54]. In dysplastic hips with deficient acetabular coverage, the iliocapsularis has been observed to be more prominent and hypertrophied. Conversely, the iliocapsularis is frequently diminutive and atrophied in stable hips with adequate acetabular coverage. Using MRI to define the iliocapsularis has been described as a useful preoperative decision-making tool in assessing hip stability in patients with borderline hip dysplasia [23]. MRI assessment of the iliocapsularis utilizes the axial T1-weighted image to define both the muscle morphology and degree of fatty infiltration at two points (4 cm below the AIIS and on first section inferior to the femoral head). Patients with deficient acetabular coverage were observed to have increased thickness, width, circumference, cross-sectional area, and partial volume of the iliocapsularis muscle and decreased fatty infiltration.

Imaging Clusters

We recently reviewed the comprehensive preoperative radiographic parameters of patients undergoing hip preservation surgery with “mild” or “borderline” dysplasia (LCEA 18–25°) at a tertiary referral center [35]. Ninety-nine patients underwent either hip arthroscopy or PAO over a 5-year period, and their preoperative imaging was reviewed for LCEA, Tonnis Angle, AWI/PWI, ACEA, FNSA, Alpha Angle (AP and Dunn views), and FEAR Index.

A cluster analysis was performed in an attempt to identify certain morphological groups within the overall patient cohort. We noted that males and females had fairly distinct morphologies, so sex-specific cluster analyses were performed. The cluster groups are presented in Table 2. Male patients showed 3 morphologic clusters: global impingement (high alpha angle on AP/Dunn and low PWI), focal impingement (high alpha angle on Dunn and low PWI), and isolated lateral acetabular insufficiency (low LCEA). Female patients also had 3 morphologic clusters: impingement (high alpha angle on AP/Dunn), anterolateral acetabular deficiency (low LCEA, low AWI, low ACEA, high FEAR), and isolated lateral acetabular insufficiency (low LCEA).

Table 2 Male and female borderline acetabular dysplasia categories based upon radiographic parameters. AP, anteroposterior; LCEA, lateral center edge angle; ACEA, anterior center edge angle; AWI, anterior wall index

Using these patient clusters as a baseline, a reconsideration of the available literature is appropriate. Three patient clusters, two in males (global impingement and focal impingement) and one in females (impingement) had morphological features consistent with femoroacetabular impingement. These clusters were specifically targeted in the study by Nawabi et al., who described the outcomes of hip arthroscopy for cam resection and capsulolabral repair in patients with LCEA 18–25° [40]. They noted results comparable to those found in patients with normal acetabular coverage undergoing arthroscopic cam resection.

The anterolateral acetabular deficiency cluster in females showed numerous features of acetabular dysplasia. Not uncommonly, the borderline LCEA measurement was their most normal acetabular feature, and their anterior coverage was consistently suboptimal. A recent study noted that inadequate anterior acetabular coverage was predictive of poor outcomes following hip arthroscopy [25]. Two recent studies on PAO outcomes in patients with borderline dysplasia showed significant functional improvements with low rates of complications and failures at short-term follow-up [34, 45]. One of these studies noted that the majority of PAO patients had numerous radiographic features of dysplasia aside from LCEA measurement, and that anterior coverage was the most commonly deficient region [34••].

Conclusions

The management of borderline dysplasia is an active controversy in the field of hip preservation. Much of the literature, up to this point, has isolated the definition of borderline dysplasia to the LCEA measurement. As awareness of the variable deformities present in acetabular dysplasia increases, isolated reliance on measurement of lateral femoral head coverage to define severity of undercoverage will continue to mislabel patients. Future studies should strive to more thoroughly define the characteristics of mild acetabular undercoverage, which will enable meaningful comparative effectiveness studies between hip arthroscopy and periacetabular osteotomy in the treatment of acetabular dysplasia in these patients. These studies can strive to help identify the patient subgroups to treat with either a hip arthroscopy or periacetabular osteotomy.