Abstract
We report the synthesis and characterization of crystalline calcium phosphate (CaP) nanostructures from calcium inositol hexakisphosphate (CaIP6) precursor in water-ethanol mixed solutions. We show how these CaPs can be prepared by a solvo-hydrothermal reaction and determined their compositions and structures using a battery of material characterization techniques. Our results show that only the hydroxyapatite (HAP) and dicalcium phosphate anhydrous (DCPA) phases of CaP were present in the nanostructures produced in water-ethanol mixtures, and that HAP/DCPA ratio of the rod- and plate-shaped CaP nanostructures produced were affected by the amount of ethanol present in these mixtures. The described method can be used to improve morphological control of CaP-based biomate-rials and has potential use in bone regenerative medicine.
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Acknowledgements
This work was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Education, Korea (NRF-2015R1D1A1 A01059580 and NRF-2019R1F1A1060060), by the Nano-Material Technology Development Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning (2009–0082580), and by the Basic Core TechTechnology Development Program for the Oceans and the Polar Regions of the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (NRF-2015M1A5A1037054).
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Solvo-hydrothermal synthesis of calcium phosphate nanostructures from calcium inositol hexakisphosphate precursor in water-ethanol mixed solutions
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Han, JH., Pack, S.P. & Chung, S. Solvo-hydrothermal synthesis of calcium phosphate nanostructures from calcium inositol hexakisphosphate precursor in water-ethanol mixed solutions. Korean J. Chem. Eng. 37, 891–897 (2020). https://doi.org/10.1007/s11814-020-0496-3
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DOI: https://doi.org/10.1007/s11814-020-0496-3