Abstract
Copper(ii) and manganese(ii) chelate complexes were synthesized using the new N,O-hybrid ligand 1,3-dibenzhydryl-5-(pyridin-2-yl)-1,3,5-diazaphosphinane 5-oxide. The synthesized complexes were characterized by physicochemical methods. The molecular and crystal structures of the complexes were established by X-ray diffraction. All new compounds were evaluated for cytotoxicity against the cancer cell lines M-HeLa and HuTu80 and the normal cell line Chang liver.
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Dedicated to Academician of the Russian Academy of Sciences V. I. Ovcharenko on the occasion of his 70th birthday.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 7, pp. 1410–1421, July, 2022.
The measurements were carried out using the equipment of the Assigned Spectral-Analytical Center of Shared Facilities for Study of Structure, Composition and Properties of Substances and Materials of the FRC Kazan Scientific Center of the Russian Academy of Sciences.
No human or animal subjects were used in this research.
The authors declare no competing interests.
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Trigulova, K.R., Shamsieva, A.V., Kasimov, A.I. et al. Copper(ii) and manganese(ii) complexes based on a new N,O-chelating ligand bearing the 1,3,5-diazaphosphorinane moiety. Russ Chem Bull 71, 1410–1421 (2022). https://doi.org/10.1007/s11172-022-3547-6
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DOI: https://doi.org/10.1007/s11172-022-3547-6