Abstract
A general approach to the synthesis of new 3-acetyl-substituted pyrrolo[3,4-f]indole-5,7-diones, 3-[3-(dimethylamino)acryloyl]-1-methoxypyrrolo[3,4-f]indole-5,7-diones and similar indole-5,6-dicarbonitriles has been developed. Dimethylaminoacryloyl derivatives synthesized on their basis regioselectively reacted with hydrazine hydrochlorides and hydroxylamine with the formation of the corresponding 5-substituted azoles.
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 6, pp. 1018—1023, June, 2017.
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Chirkova, Z.V., Filimonov, S.I. & Abramov, I.G. Synthesis of substituted 3-acyl-1-hydroxyindoles and azoles on their basis. Russ Chem Bull 66, 1018–1023 (2017). https://doi.org/10.1007/s11172-017-1849-x
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DOI: https://doi.org/10.1007/s11172-017-1849-x