We build a novel fluorescence resonance energy transfer (FRET) method based on N-doped graphene quantum dots (NGQDs)–MnO2 nanocomposite for rapid, sensitive detection of glutathione (G SH) levels in human serum. In this strategy, MnO2 nanosheets on the NGQDs surface serve as a quencher. NGQDs fluorescence can make a recovery by the addition of GSH, which can reduce MnO2 to Mn2+, and thus the GSH can be monitored. The MnO2 platform affords minimal background and high sensitivity for detecting GSH in this proposed scheme. Meanwhile, relevant fluorescence on–off–on processes were monitored, and the sensing mechanism was explored.
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Abstract of article is published in Zhurnal Prikladnoi Spektroskopii, Vol. 87, No. 5, p. 849, September–October, 2020.
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Li, ZM., Pi, T., Sheng, YP. et al. Fluorescence Detection of Glutathione Using N-Doped Graphene Quantum Dots–MnO2 Nanoarchitecture. J Appl Spectrosc 87, 930–937 (2020). https://doi.org/10.1007/s10812-020-01091-2
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DOI: https://doi.org/10.1007/s10812-020-01091-2