Differentiation of T cells was studied in the progeny of female C57Bl/6 mice subjected to immunostimulation by administration of concanavalin A or adoptive transfer of concanavalin A-activated splenocytes. Acceleration of T cell maturation during the prepubertal period and decelerated differentiation during the pubertal and post-pubertal periods were revealed.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
S. S. Obernikhin and N. V. Yaglova, Ross. Immunol. Zh., 8, No. 1, 10-15 (2014).
N. V. Yaglova and S. S. Obernikhin, Klin. Eksp. Morfol., No. 2, 62-68 (2013).
A. L. Fowden, D. A. Giussani, and A. J. Forhead, Physiology (Bethesda), 21, 29-37 (2006).
A. J. George and M. A. Ritter, Immunol. Today, 17, No. 6, 267-272 (1996).
R. N. Germain, Nat. Rev. Immunol., 2, No. 5, 309-322 (2002).
J. Gordon and N. R. Manley, Development, 138, No. 18, 3865-3878 (2011).
N. A. Hodyl, M. J. Stark, A. Osei-Kumah, and V. L. Clifton, Expert Rev. Clin. Immunol., 7, No. 5, 579-592 (2011).
A. C. Huizink, E. J. Mulder, and J. K. Buitelaar, Psychol. Bull., 130, No. 1, 115-142 (2004).
A. Singer, S. Adoro, and J. H. Park, Nat. Rev. Immunol., 8, No. 10, 788-801 (2008).
M. J. Warner and S. F. Ozanne, Biochem. J., 427, No. 3, 333-347 (2010).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 160, No. 11, pp. 613-616, November, 2015
Rights and permissions
About this article
Cite this article
Yaglova, N.V., Obernikhin, S.S. Changes in Differentiation of Thymic T Cells in the Progeny of Female Mice Subjected to Immune System Stimulation during Early Pregnancy. Bull Exp Biol Med 160, 664–667 (2016). https://doi.org/10.1007/s10517-016-3244-2
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-016-3244-2