Abstract
Elaeagnus umbellata is a plant that grows in the hilly areas of Pakistan. Free radical scavenging activities and anti-lipid peroxidative properties of hot water, methanol, n-hexane, and acetone extracts of E. umbellata berries were evaluated. Extracts showed inhibition against thiobarbituric acid reactive species (TBARS) induced using the pro-oxidants iron (10 μM FeSO4) and sodium nitroprusside (5 μM) in brain and liver homogenates of mice. Extracts also showed metal chelating activities of IC50 (extract concentration that causes 50% scavenging)=40–43 μg/mL and DPPH radical scavenging activities of IC50=45.4–49 μg/mL. HPLC analysis revealed the presence of gallic, vanillic, coumaric, ferulic, sinapic, and caffeic acids in berries. The fruit of E. umbellata is a potential source of antioxidants with therapeutic importance.
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Ishaq, S., Rathore, H.A., Sabir, S.M. et al. Antioxidant properties of Elaeagnus umbellata berry solvent extracts against lipid peroxidation in mice brain and liver tissues. Food Sci Biotechnol 24, 673–679 (2015). https://doi.org/10.1007/s10068-015-0088-x
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DOI: https://doi.org/10.1007/s10068-015-0088-x