Abstract
Edward Mason introduced a different approach to bariatric surgery (BS) in 1966, inspired by the observation that subtotal gastrectomies often cause weight loss (WL) [1]. The first gastric bypass procedure was performed by horizontal section of 10% volume of the upper stomach and anastomosis into the jejunal loop, excluding 90% of the gastric reservoir. Wittgrove and Clark established a standard technique for laparoscopic gastric bypass in 1991 [2]. Similar progressive improvement in the results of Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) is reported in most large series around the world [3, 4].
You have full access to this open access chapter, Download chapter PDF
Similar content being viewed by others
Introduction
Edward Mason introduced a different approach to bariatric surgery (BS) in 1966, inspired by the observation that subtotal gastrectomies often cause weight loss (WL) [1]. The first gastric bypass procedure was performed by horizontal section of 10% volume of the upper stomach and anastomosis into the jejunal loop, excluding 90% of the gastric reservoir. Wittgrove and Clark established a standard technique for laparoscopic gastric bypass in 1991 [2]. Similar progressive improvement in the results of Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) is reported in most large series around the world [3, 4].
BS or Metabolic Surgery (MS) has given morbidly obese patients sustainable WL and better or complete control of weight-related comorbidities like Type 2 Diabetes Mellitus (T2DM), hypertension (HT), hyperlipidemia (HL), obstructive sleep apnea, joint pain, and others. Laparoscopic Roux-en-Y (LRYGB) is considered the gold standard BS procedure giving the above benefits for a longer period of time. LRYGB is also associated with lifelong follow-up like other bariatric surgeries and requires stringent intake of multivitamins, calcium tablets, vitamin d supplements, and Iron for long periods of time to prevent nutrition-related side effects a few years down the line.
With LRYGB method, up to 25% total body WL (68.2% excess WL) can be achieved in the long term [5, 6]. After LRYGB, WL was attributed to consuming a smaller volume and bypassing the jejunum. However, it is likely that there is a complex interplay of physiological mechanisms including food intake, food preferences, calorie restriction, and energy expenditure.
Early complications occur in approximately 4% of patients after LRYGB. The most common complications are bleeding, perforation, or leakage requiring immediate surgical intervention [7]. In 15–20% of patients, late complications such as abdominal pain, obstruction, anastomotic stricture, and marginal ulcers may occur up to 10 years after surgery [8, 9].
Patient Selection and Indications
Medical treatment can be tried in morbid obesity, but failure rates are still very high, patients can be evaluated for surgery after medical treatment fails. NIH has determined some conditions for patients who want to have BS in 1991 [10]. The Society of American Gastrointestinal Endoscopic Surgeons (SAGES) has similar recommendations [11].
-
Patients who are unlikely to respond to medical treatment.
-
Patients who are motivated and informed about surgical risks.
-
Patients with a body mass index (BMI)Â >Â 40Â kg/m2.
-
Patients with BMI between 35 and 40Â kg/m2, with one high-risk comorbid condition.
In Asian setup, the following guidelines are followed
-
BMI >37Â kg/m2 irrespective of comorbidity.
-
BMI >32Â kg/m2 in the presence of T2DM or two or more obesity-related comorbidities.
These guidelines ensure that patients can be properly classified for surgery, and patients can be prepared for surgery.
Contraindications
-
Contraindications of General Anesthesia.
-
Intractable Coagulopathy.
-
Metastatic or Inoperable Malignancy.
-
Cirrhosis with Portal Hypertension (Type B and C Budd Chiari Classification).
-
Inflammatory Bowel Disease.
-
Previous Surgery involving small bowel resection.
-
Relative contraindications include large ventral hernia, multiple previous abdominal surgeries, extremes of age (<18 and >65), alcohol/drug abuse.
Note: Surgery should be deferred if the patient plans for pregnancy within 12–18 months.
Preoperative Assessment
The most important aspect for long-term success of LRYGB is proper counseling regarding lifestyle and dietary changes, regular follow-ups, and need for prolonged supplement usage.
Preoperative Investigation
Blood Investigation
Complete blood count, Blood Group, Renal Function Test, Liver Function test, PT/INR, PTTK, Lipid Profile, Thyroid Profile, Blood sugar random (Blood sugar Fasting and Postprandial, HbA1C, C peptide level if Diabetic), Vitamin B12, and Vitamin D3.
-
1.
X-ray Chest.
-
2.
ECG and 2D ECHO or 2D Stress Echo (If hypertensive).
-
3.
Upper Gastrointestinal Endoscopy (to rule out H. Pylori Infection).
-
4.
Ultrasound Examination of whole abdomen (to rule out gall stones) and if present Cholecystectomy should be planned with bariatric even if asymptomatic.
-
5.
Urine Routine and Microscopy.
-
6.
Ultrasound Doppler Bilateral Lower Limb Venous System (to rule out DVT).
OT Setup and Port Positioning
Patient’s Position
All long instruments, Nathanson’s Liver Retractor, and 45°long scope should be ready. Patient should be in Supine position or split leg according to surgeon preference with secure strapping and padding of bony points and table should be checked for reverse Trendelenburg position. We catheterize all patients routinely. (Fig. 1).
Port Positioning
Our preferred entry is by 0 telescope mounted on 12 mm 15 cm long Optiview trocar in the left midclavicular line 15–18 cm from Epigastrium.
-
1.
Second Trocar is inserted 5 or 12 mm 15–18 cm from epigastrium in right midclavicular line (Surgeon port).
-
2.
Third 12 mm trocar is inserted a palm breadth from second trocar in right upper abdomen (Surgeon port).
-
3.
Fourth 5 mm port through epigastrium for liver retractor.
-
4.
Fifth 5 mm port palm breadth from first on left upper abdomen (Assistant Port) (Fig. 1b).
Surgical Technique
-
Step 1: Creation of gastric pouch: Patient is placed in steep reverse Trendelenburg position. Dissection is done along lesser curvature starting between first and second vessel from gastroesophageal junction. A retrogastric tunnel is created by blunt dissection and energy source. A 60 mm linear blue or purple stapler applied transversely from port 3 and followed by Vertical 60 mm Blue or Purple firings [2–3] from port 2 to create 25–30 ml pouch is created over 36 french bougies. Gastrotomy is created at distal most part of the pouch for Gastrojejunostomy (Fig. 2).
-
Step 2: Fashioning of Gastrojejejunostomy: Patient is made supine. Transverse Mesocolon mesentery is lifted to identify DJ Flexure (Ligament of Treitz) and small bowel is counted 70–100 cm (Depending on BMI kg/m2) and 45 cm blue or purple stapler is used and Gastrojejunostomy is fashioned and enterotomy closed by vicryl 2/0 after performing Jejuno-jejunostomy. Now Patient is again made reverse Trendelenburg. The patency of Gastrojejunostomy is checked by smooth passage of Orogastric Tube. Leakage is checked by methylene blue dye test (Fig. 3).
-
Step 3: Side to Side Jejuno-Jejunostomy: 60 mm white stapler is used to form BilioPancreatic limb just distal to Gastrojejunostomy. Now 100 cm Alimentary Limb is counted and Side to side Jejuno-Jejunostomy is fashioned by 60 mm white stapler and enterotomy closed by vicryl 2/0 (Fig. 4).
-
Step 4: Closure of Mesenterc defects: Both Jejeunojejunostomy and Petersen defects are closed by nonabsorbable 2/0 Ethibond sutures.
-
Step 5: Drain Insertion and closure of defects: One Jackson Pratt drain is put close to Gastrojejunostomy anastomosis and all ports are closed (12 mm ports are closed in layers and 5 mm only skin is closed).
Post-op Course
Patient is kept NPO on the day of surgery and put on pantoprazole infusion (80 mg in 50 ml normal saline at 5 ml/h). Patient is started on oral sips on post-op day1 and mobilized with chest physiotherapy and Incentive spirometry. On postoperative day 2 30–50 ml clear liquid is started and the patient is discharged with one dose of protein solution. Gradually Clear liquid fluid is escalated to 80–100 ml per hour followed by blend diet and full small meals over a period of 1–2 months. Note patient should not drink water 30 min before and 30 min after every meal. Patient should not use any straw. Most important is complete abstinence from Alcohol and Smoking to prevent any complications. Another important point is the continuous intake of multivitamins, Calcium, VitaminD3, and Iron throughout life. Patient is also advised for complete laboratory checks once a year and monthly meetings with the physician and should be encouraged to attend support group meetings.
Common Complications
-
Bleeding: Any evidence of bleeding like disproportionate rise in pulse rate and drop in hemoglobin should warn for diagnostic laparoscopy even in absence of any abdominal signs. CECT abdomen may be used as an adjunct for relaparoscopy but should not be mandatory and clinical suspicion should alert the clinician to have a diagnostic check. Any bleeder should be sutured (over hemostat) and if no bleeding is seen, check endoscopy intraoperative should be done and bleeder taken care of. If still no bleeder is seen and jejeuno-jejunostomy is suspected oversewing the anastomosis and if required refashioning the anastomosis should be considered.
-
Leakage: Another very important complication is leakage from anastomotic site. Re Laparoscopy with resuturing/refashioning anastomosis/Gastrostomy drainage with feeding jejeunostomy should be attempted depending on the time of redo surgery and patient general condition. Leakage from Jejeuno-jejunostomy should be dealt with suturing/refashioning with distal feeding jejunostomy should be done.
-
Stenosis: Gastrojejunostomy stricture should be dealt with the removal of triggering factor (Smoking) and serial dilatations or refashioning. Jejuno-jejunostomy stricture will present with obstruction or abdominal distension and will require refashioning.
-
Others: Deep Venous Thrombosis and Pulmonary embolism should be dealt with standard treatment protocols. Weight regain treatment will vary from diet counseling, redosurgery (Limb lengthening/fundectomy). Internal hernias are rare if both mesenteries are closed but if any doubt exists immediate Diagnostic laparoscopy or Exploratory Laparotomy should be done. Nutritional deficiencies have to be dealt with on case to case basis and may even require reversal of procedure in extreme cases.
Late Complications
-
Vitamin deficiencies and hair loss.
-
Dental problems.
-
Abdominal pain and discomfort.
-
Dumping syndrome.
-
Postprandial hypoglycemia.
-
Loss of bone density.
-
Kidney stones.
-
Gallstones.
-
Gastric remnant distension.
-
Marginal ulcers.
-
Stomal Stenosis [12].
Conclusion
LRYGB offers both benefits and complications, the mechanisms of which are still not fully understood. Most clinicians agree that beneficial effects outweigh harm [13, 14]. The suggestions that the LRYGB relies solely on mechanical restriction and malabsorption are no longer valid. In order to achieve positive results after LRYGB, the harmony of intestinal hormones, bile acids, nerve mechanisms, intestinal microbiota, food preferences and changes in energy expenditure is essential [15]. Complications can be seen in all bariatric surgical methods. However, many studies have been conducted in order to diagnose complications early and manage them correctly after LRYGB.
References
Mason EE, Ito C. Gastric bypass in obesity. Surg Clin N Am. 1967;47(6):1345–51.
Wittgrove AC, Clark GW, Schubert KR. Laparoscopic gastric bypass, Roux en-Y: technique and results in 75 patients with 3-30 months follow-up. Obes Surg. 1996;6(6):500–4.
Weiss AC, Parina R, Horgan S, Talamini M, Chang DC, Sandler B. Quality and safety in obesity surgery—15 years of Roux-en-Y gastric bypass outcomes from a longitudinal database. Surg Obes Relat Dis. 2016;12(1):33–40.
Maciejewski ML, Livingston EH, Smith VA, Kavee AL, Kahwati LC, Henderson WG, Arterburn DE. Survival among high-risk patients after bariatric surgery. JAMA. 2011;305(23):2419–26.
Olbers T, Gronowitz E, Werling M, Mårlid S, Flodmark CE, Peltonen M, Marcus C. Two-year outcome of laparoscopic Roux-en-Y gastric bypass in adolescents with severe obesity: results from a Swedish Nationwide study (AMOS). Int J Obes. 2012;36(11):1388–95.
Buchwald H, Avidor Y, Braunwald E, Jensen MD, Pories W, Fahrbach K, Schoelles K. Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004;292(14):1724–37.
Hofmann W, van Koningsbruggen GM, Stroebe W, Ramanathan S, Aarts H. As pleasure unfolds: hedonic responses to tempting food. Psychol Sci. 2010;21(12):1863–70.
Abdeen G, Le Roux CW. Mechanism underlying the weight loss and complications of Roux-en-Y gastric bypass. Rev Obes Surg. 2016;26(2):410–21.
Franco J, Ruiz P, Palermo M, Gagner M. A review of studies comparing three laparoscopic procedures in bariatric surgery: sleeve gastrectomy, Roux-en-Y gastric bypass and adjustable gastric banding. Obes Surg. 2011;21:1458–68.
Consensus Development Conference Panel. Gastrointestinal surgery for severe obesity. Ann Intern Med. 1991;115(12):956–61.
Nguyen NT, DeMaria E, Ikramuddin S. In: Hutter MM, editor. The SAGES manual: a practical guide to bariatric surgery. Springer Science & Business Media; 2008.
le Roux CW, Sinclair P. Gastric bypass: mechanisms of functioning, In gastric bypass. Cham: Springer; 2020. p. 7–21.
Abdeen G, Le Roux CW. Mechanism underlying the weight loss and complications of Roux-en-Y gastric bypass. Review. Obesity surgery. 2016;26(2):410–21.
Pinkney J. Consensus at last? The international diabetes federation statement on bariatric surgery in the treatment of obese type 2 diabetes. Diabet Med. 2011;28(8):884–5.
le Roux CW, Welbourn R, Werling M, Osborne A, Kokkinos A, Laurenius A, Olbers T. Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass. Ann Surg. 2007;246(5):780–5.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Open Access This chapter is licensed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.
The images or other third party material in this chapter are included in the chapter's Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the chapter's Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
Copyright information
© 2023 The Author(s)
About this chapter
Cite this chapter
Goel, R., Huang, CK., Guldogan, C.E. (2023). Laparoscopic Roux EN y Gastric Bypass (LRYGB). In: Lomanto, D., Chen, W.TL., Fuentes, M.B. (eds) Mastering Endo-Laparoscopic and Thoracoscopic Surgery. Springer, Singapore. https://doi.org/10.1007/978-981-19-3755-2_42
Download citation
DOI: https://doi.org/10.1007/978-981-19-3755-2_42
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-19-3754-5
Online ISBN: 978-981-19-3755-2
eBook Packages: MedicineMedicine (R0)