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Regenerative Nanotechnology: Engineered Surfaces for Stem Cell Production

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Nanomedicine

Part of the book series: Micro/Nano Technologies ((MNT))

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Abstract

Recent advances in stem cell biology have opened a way to treat patients suffering from traumatic injuries and degenerative disorders in various tissues and organs. However, the widespread clinical applications of this new methodology require a further technological advances in the production and quality control of cells, the optimization of cellular microenvironments in the host tissues, and the noninvasive tracking of transplanted cells and their behaviors. It is often that these challenges are the topic of nanotechnology research around the world. Among these challenges, this chapter is specially directed to introduce nanotechnological approaches to develop efficient methods for stem cell production. A special attention will be paid to the biologically active substrates on which one can selectively and rapidly expand stem cell populations. Another focus of this chapter includes the utilization of genetically engineered building blocks for the nanoscale molecular design of bioactive surfaces. It will be emphasized that genetic engineering can be an attractive tool for precisely and rationally designing proteinaceous components of biomaterials and devices.

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Author information

Authors and Affiliations

  1. Department of Biomaterials, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan

    Ayana Nakano & Koichi Kato

  2. Department of Orthodontics and Craniofacial Developmental Biology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan

    Ayana Nakano

  3. Nanomedicine Research Division, Research Institute for Nanodevices, Hiroshima University, Hiroshima, Japan

    Koichi Kato

Authors
  1. Ayana Nakano
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  2. Koichi Kato
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Corresponding author

Correspondence to Koichi Kato .

Editor information

Editors and Affiliations

  1. School of Biomedical Sci. & Medical Eng., Southeast University, Nanjing, China

    Ning Gu

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Nakano, A., Kato, K. (2022). Regenerative Nanotechnology: Engineered Surfaces for Stem Cell Production. In: Gu, N. (eds) Nanomedicine. Micro/Nano Technologies. Springer, Singapore. https://doi.org/10.1007/978-981-13-9374-7_20-1

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  • DOI: https://doi.org/10.1007/978-981-13-9374-7_20-1

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-13-9374-7

  • Online ISBN: 978-981-13-9374-7

  • eBook Packages: Springer Reference EngineeringReference Module Computer Science and Engineering

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