Zusammenfassung
Die arterielle Hypertonie ist ein bedeutender kardiovaskulärer Risikofaktor, dessen Diagnostik und Therapie weltweit von immenser gesundheitlicher und sozioökonomischer Relevanz ist. Eine arterielle Hypertonie liegt definitionsgemäß bei einem systolischen Wert ≥140 mmHg und/oder einem diastolischen Wert ≥90 mmHg vor. Neben der Praxisblutdruckmessung sollte die Diagnose mittels praxisunabhängiger Messungen überprüft werden. Pathophysiologisch ist häufig eine gesteigerte Aktivität des Renin-Angiotensin-Aldosteron-Systems mit konsekutiv gesteigertem Sympathikotonus ursächlich für die Entwicklung einer arteriellen Hypertonie. Dies bildet die Grundlage von wesentlichen medikamentösen und interventionellen Behandlungsansätze. Eine Vielzahl von klinischen Studien konnte bisher deren positiven prognostischen Effekt untermauern. Das folgende Buchkapitel bietet – basierend auf aktuellen Leitlinienempfehlungen – einen Überblick über die Definition der arteriellen Hypertonie, deren Diagnostik und Therapie.
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Emrich, I., Kulenthiran, S., Mahfoud, F. (2022). Kardiovaskulärer Risikofaktor Hypertonie. In: Marx, N., Erdmann, E. (eds) Klinische Kardiologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-62939-0_8-1
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