Skip to main content
SpringerLink
Log in

Prostatakarzinom: Kurative Therapie

  • Chapter
  • First Online:
Die Urologie

Part of the book series: Springer Reference Medizin ((SRM))

  • 786 Accesses

Zusammenfassung

Etablierte kurative Therapieoptionen des frühen Prostatakarzinoms sind die radikale Prostatektomie, die perkutane Strahlentherapie, die interstitielle Brachytherapie und die aktive Überwachung. Im Gegensatz zum palliativen und symptomorientierten Watchful Waiting wird darunter die genaue Tumorüberwachung mit Hilfe von Kontrollbiopsien in kurativer Absicht auch bei Tumorprogress verstanden. Aussagefähige Ergebnisse randomisierter Studien, die die 4 kurativen Therapieoptionen miteinander vergleichen, liegen noch nicht vor. Die Behandlungsverfahren unterscheiden sich hinsichtlich ihrer Nebenwirkungen. Als adjuvante Therapieverfahren stehen die Androgenentzugstherapie und bei der radikalen Prostatektomie die adjuvante Strahlentherapie zur Verfügung. Die neoadjuvante Hormontherapie hat eine Bedeutung überwiegend bei der perkutanen Strahlentherapie des lokal fortgeschrittenen Prostatakarzinoms. Vor einer radikalen Prostatektomie kommt sie nur im individuellen Sonderfall im Rahmen multimodaler Therapiekonzepte zur Anwendung. Bei rechtzeitiger Anwendung kann eine Salvage-Strahlentherapie einen Teil der Patienten mit einem PSA-Anstieg nach radikaler Prostatektomie (biochemisches Rezidiv) heilen.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 269.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

Literatur

  • Ahmed HU, Ishaq A, Zacharakis E, Shaw G, Illing R, Allen C, Kirkham A, Emberton M (2009) Rectal fistulae after salvage high-intensity focused ultrasound for recurrent prostate cancer after combined brachytherapy and external beam radiotherapy. BJU Int 103:321–323

    Article  PubMed  Google Scholar 

  • Becker A, Tennstedt P, Hansen J, et al (2013) Functional and oncological outcomes of patients younger than 50 years treated with radical prostatectomy for localized prostate cancer in a European population. BJU Int (im Druck)

    Google Scholar 

  • Bian SX, Hoffman KE (2013) Management of prostate cancer in elderly men. Semin Radiat Oncol 23(3):198–205

    Article  PubMed  Google Scholar 

  • Bill-Axelson A, Holmberg L, Ruutu M, Garmo H, Stark JR, Busch C, Nordling S, Häggman M, Andersson SO, Bratell S, Spångberg A, Palmgren J, Steineck G, Adami HO, Johansson JE, SPCG-4 Investigators (2011) Radical prostatectomy versus watchful waiting in early prostate cancer. N Engl J Med 364:1708–1717

    Article  CAS  PubMed  Google Scholar 

  • Bolla M, Collette L, Blank L, Warde P, Dubois JB, Mirimanoff RO, Storme G, Bernier J, Kuten A, Sternberg C, Mattelaer J, Lopez Torecilla J, Pfeffer JR, Lino Cutajar C, Zurlo A, Pierart M (2002) Long-term results with immediate androgen suppression and external irradiation in patients with locally advanced prostate cancer (an EORTC study): a phase III randomised trial. Lancet 360:103–106

    Article  CAS  PubMed  Google Scholar 

  • Bolla M, de Reijke TM, Van Tienhoven G, Van den Bergh AC, Oddens J, Poortmans PM, Gez E, Kil P, Akdas A, Soete G, Kariakine O, van der Steen-Banasik EM, Musat E, Piérart M, Mauer ME, Collette L, EORTC Radiation Oncology Group and Genito-Urinary Tract Cancer Group (2009) Duration of androgen suppression in the treatment of prostate cancer. N Engl J Med 360:2516–2527

    Article  CAS  PubMed  Google Scholar 

  • Briganti A, Karnes RJ, Da Pozzo LF, Cozzarini C, Capitanio U, Gallina A, Suardi N, Bianchi M, Tutolo M, Salonia A, Di Muzio N, Rigatti P, Montorsi F, Blute M (2011) Combination of adjuvant hormonal and radiation therapy significantly prolongs survival of patients with pT2–4 pN+ prostate cancer: results of a matched analysis. Eur Urol 59:832–840

    Article  CAS  PubMed  Google Scholar 

  • Catalona WJ, Carvalhal GF, Mager DE, Smith DS (1999) Potency, continence and complication rates in 1,870 consecutive radical retropubic prostatectomies. J Urol 162:433–438

    Article  CAS  PubMed  Google Scholar 

  • Chin JL, Al-Zahrani AA, Autran-Gomez AM, Williams AK, Bauman G (2012) Extended followup oncologic outcome of randomized trial between cryoablation and external beam therapy for locally advanced prostate cancer (T2c–T3b). J Urol 188:1170–1175

    Article  PubMed  Google Scholar 

  • Coelho RF, Chauhan S, Orvieto MA, Sivaraman A, Palmer KJ, Coughlin G, Patel VR (2011) Influence of modified posterior reconstruction of the rhabdosphincter on early recovery of continence and anastomotic leakage rates after robot-assisted radical prostatectomy. Eur Urol 59:72–80

    Article  PubMed  Google Scholar 

  • Crook J, Ots AF (2013) Prognostic factors for newly diagnosed prostate cancer and their role in treatment selection. Semin Radiat Oncol 23(3):165–172

    Article  PubMed  Google Scholar 

  • Crouzet S, Chapelon JY, Rouvière O, Mege-Lechevallier F, Colombel M, Tonoli-Catez H, Martin X, Gelet A (2013) Whole-gland ablation of localized prostate cancer with high-intensity focused ultrasound: oncologic outcomes and morbidity in 1002 patients. Eur Urol 65:907–914 (Epub vor Druck)

    Article  PubMed  Google Scholar 

  • Da Pozzo LF, Cozzarini C, Briganti A, Suardi N, Salonia A, Bertini R, Gallina A, Bianchi M, Fantini GV, Bolognesi A, Fazio F, Montorsi F, Rigatti P (2009) Long-term follow-up of patients with prostate cancer and nodal metastases treated by pelvic lymphadenectomy and radical prostatectomy: the positive impact of adjuvant radiotherapy. Eur Urol 55(5):1003–1011

    Article  PubMed  Google Scholar 

  • D’Amico AV, Whittington R, Malkowicz SB, Schultz D, Blank K, Broderick GA, Tomaszewski JE, Renshaw AA, Kaplan I, Beard CJ, Wein A (1998) Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer. JAMA 280(11):969–974

    Article  PubMed  Google Scholar 

  • Denham JW, Steigler A (2013) Picking the optimal duration of hormonal therapy in men with high-risk and locally advanced prostate cancer treated with radiotherapy. Semin Radiat Oncol 23(3):206–214

    Article  PubMed  Google Scholar 

  • Denham JW, Joseph D, Lamb DS, Spry NA, Duchesne G, Matthews J et al (2014) Short-term androgen suppression and radiotherapy versus intermediate-term androgen suppression and radiotherapy, with or without zoledronic acid, in men with locally advanced prostate cancer (TROG 03.04 RADAR): an open-label, randomised, phase 3 factorial trial. Lancet Oncol 15:1076–1089

    Article  CAS  PubMed  Google Scholar 

  • Deutsche Gesellschaft für Urologie e. V.: Interdisziplinäre Leitlinie der Qualität S3 zur Früherkennung, Diagnose und Therapie der verschiedenen Stadien des Prostatakarzinoms. Version 2.0 – 1. Aktualisierung 2011. Verfügbar auf der Website der Deutschen Gesellschaft für Urologie (DGU): http://www.urologenportal.de/fileadmin/MDB/PDF/S3_LL_PCAS3_PCa_Aktualisierung_2011_110912f.pdf. Zugegriffen am 29. 07 2013

  • Eggener SE, Scardino PT, Walsh PC, Han M, Partin AW, Trock BJ, Feng Z, Wood DP, Eastham JA, Yossepowitch O, Rabah DM, Kattan MW, Yu C, Klein EA, Stephenson AJ (2011) Predicting 15-year prostate cancer specific mortality after radical prostatectomy. J Urol 185:869–875

    Article  PubMed  PubMed Central  Google Scholar 

  • Eifler JB, Feng Z, Lin BM, Partin MT, Humphreys EB, Han M, Epstein JI, Walsh PC, Trock BJ, Partin AW (2013) An updated prostate cancer staging nomogram (Partin tables) based on cases from 2006 to 2011. BJU Int 111(1):22–29

    Article  PubMed  Google Scholar 

  • Elterman DS, Barkin J, Radomski SB, Fleshner NE, Liu B, Bensimon K, Arora S, Robinette M, Finelli A (2011) Results of high intensity focused ultrasound treatment of prostate cancer: early Canadian experience at a single center. Can J Urol 18:6037–6042

    PubMed  Google Scholar 

  • Ficarra V, Novara G, Rosen RC, Artibani W, Carroll PR, Costello A, Menon M, Montorsi F, Patel VR, Stolzenburg JU, Van der Poel H, Wilson TG, Zattoni F, Mottrie A (2012) Systematic review and meta-analysis of studies reporting urinary continence recovery after robot-assisted radical prostatectomy. Eur Urol 62:405–417

    Article  PubMed  Google Scholar 

  • Heidenreich A, Bastian PJ, Bellmunt J, Bolla M, Joniau S, Mason MD, Matveev V, Mottet N, van der Kwast TH, Wiegel T, Zattoni F. EAU guidelines on prostate cancer. Update 2013: http://www.uroweb.org/gls/pdf/08%20Prostate%20Cancer_LR%20March%2013th%202012.pdf. Zugegriffen am 08. 07. 2013

  • Herrmann T, Baumann M, Doerr W (2006) Klinische Strahlenbiologie. Elsevier, München

    Google Scholar 

  • Hoskin PJ, Colombo A, Henry A, Niehoff P, Paulsen Hellebust T, Siebert F-A, Kovacs G (2013) GEC/ESTRO recommendations on high dose rate afterloading brachytherapy for localised prostate cancer: an update. Radiother Oncol 107(3):325–332

    Article  PubMed  Google Scholar 

  • Hull GW, Rabbani F, Abbas F, Wheeler TM, Kattan MW, Scardino PT (2002) Cancer control with radical prostatectomy alone in 1000 consecutive patients. J Urol 167:528–534

    Article  PubMed  Google Scholar 

  • Keating NL, Liu PH, O'Malley AJ, Freedland SJ, Smith MR (2013) Androgen-deprivation therapy and diabetes control among diabetic men with prostate cancer. Eur Urol 65(4):816–24. doi:10.1016/j.eururo.2013.02.023

    Google Scholar 

  • Kim SC, Song C, Kim W, Kang T, Park J, Jeong IG, Lee S, Cho YM, Ahn H (2011) Factors determining functional outcomes after radical prostatectomy: robot-assisted versus retropubic. Eur Urol 60:413–419

    Article  PubMed  Google Scholar 

  • Kuban DA, Levy LB, Potters L, Beyer DC, Blasko JC, Moran BJ, Ciezki JP, Zietman AL, Zelefsky MJ, Pisansky TM, Elshaikh M, Horwitz EM (2006) Comparison of biochemical failure definitions for permanent prostate brachytherapy. Int J Radiat Oncol Biol Phys 65(5):1487–1493

    Article  CAS  PubMed  Google Scholar 

  • Kuehhas FE, Naegele R, Eckersberger E, Margreiter M, Herwig R, Kazzazi A, Djavan B (2011) Urinary continence after radical prostatectomy: the patient perspective. Can J Urol 18:5811–5818

    PubMed  Google Scholar 

  • Lepor H (2004) Radical prostatectomy: status and opportunities for improving outcomes. Cancer Invest 22:435–444

    Article  PubMed  Google Scholar 

  • Loeb S, Roehl KA, Helfand BT, Catalona WJ (2008) Complications of open radical retropubic prostatectomy in potential candidates for active monitoring. Urology 72:887–891

    Article  PubMed  Google Scholar 

  • Messing EM, Manola J, Yao J, Kiernan M, Crawford D, Wilding G, Di'SantAgnese PA, Trump D, Eastern Cooperative Oncology Group study EST 3886 (2006) Immediate versus deferred androgen deprivation treatment in patients with node-positive prostate cancer after radical prostatectomy and pelvic lymphadenectomy. Lancet Oncol 7:472–479

    Article  CAS  PubMed  Google Scholar 

  • Moul JW, Wu H, Sun L, McLeod DG, Amling C, Donahue T, Kusuda L, Sexton W, O'Reilly K, Hernandez J, Chung A, Soderdahl D (2004) Early versus delayed hormonal therapy for prostate specific antigen only recurrence of prostate cancer after radical prostatectomy. J Urol 171:1141–1147

    Article  PubMed  Google Scholar 

  • Pfister D, Bolla M, Briganti A, Carroll P, Cozzarini C, Joniau S, van Poppel H, Roach M, Stephenson A, Wiegel T, Zelefsky MJ (2013) Early salvage radiotherapy following radical prostatectomy. Eur Urol (Epub vor Druck)

    Google Scholar 

  • Pickles T, Phillips N (2002) The risk of second malignancy in men with prostate cancer treated with or without radiation in British Columbia, 1984–2000. Radiother Oncol 65(3):145–151

    Article  PubMed  Google Scholar 

  • Pisansky TM, Hunt D, Gomella LG, Amin MB, Balogh AG, Chinn DM, et al (2014) Duration of androgen suppression before radiotherapy for localized prostate cancer: radiation therapy oncology group randomized clinical trial 9910. J Clin Oncol 33(4):332–9. doi:10.1200/JCO.2014.58.0662

    Google Scholar 

  • Pound CR, Partin AW, Eisenberger MA et al (1999) Natural history of progression after PSA elevation following radical prostatectomy. JAMA 281:1591–1597

    Article  CAS  PubMed  Google Scholar 

  • Punnen S, Cooperberg MR, D’Amico AV, Karakiewicz PI, Moul JW, Scher HI, Schlomm T, Freedland SJ (2013) Management of biochemical recurrence after primary treatment of prostate cancer: A systematic review of the literature. Eur Urol 64:905–915 (Epub vor Druck)

    Article  PubMed  Google Scholar 

  • Ray ME, Thames HD, Levy LB, Horwitz EM, Kupelian PA, Martinez AA, Michalski JM, Pisansky TM, Shipley WU, Zelefsky MJ, Zietman AL, Kuban DA (2006) PSA nadir predicts biochemical and distant failures after external beam radiotherapy for prostate cancer: a multi-institutional analysis. Int J Radiat Oncol Biol Phys 64(4):1140–1150

    Article  PubMed  Google Scholar 

  • Rigatti P, Suardi N, Briganti A, Da Pozzo LF, Tutolo M, Villa L, Gallina A, Capitanio U, Abdollah F, Scattoni V, Colombo R, Freschi M, Picchio M, Messa C, Guazzoni G, Montorsi F (2011) Pelvic/retroperitoneal salvage lymph node dissection for patients treated with radical prostatectomy with biochemical recurrence and nodal recurrence detected by [11C]choline positron emission tomography/computed tomography. Eur Urol 60:935–943

    Article  PubMed  Google Scholar 

  • Rouanne M, Rode J, Campeggi A, Allory Y, Vordos D, Hoznek A, Abbou CC, La Taille AD, Salomon L (2013) Long-term impact of positive surgical margins on biochemical recurrence after radical prostatectomy: ten years of follow-up. Scand J Urol (Epub vor Druck)

    Google Scholar 

  • Sammon JD, Karakiewicz PI, Sun M, Sukumar S, Ravi P, Ghani KR, Bianchi M, Peabody JO, Shariat SF, Perrotte P, Hu JC, Menon M, Trinh QD (2013) Robot-assisted versus open radical prostatectomy: the differential effect of regionalization, procedure volume and operative approach. J Urol 189:1289–1294

    Article  PubMed  Google Scholar 

  • Scardino PT (2000) The Gordon Wilson Lecture. Natural history and treatment of early stage prostate cancer. Trans Am Clin Climatol Assoc 111:201–241

    CAS  PubMed  PubMed Central  Google Scholar 

  • Schmeller N, Keller H, Janetschek G (2007) Head-to-head comparison of retropubic, perineal and laparoscopic radical prostatectomy. Int J Urol 14:402–405

    Article  PubMed  Google Scholar 

  • Shelley MD, Kumar S, Wilt T, Staffurth J, Coles B, Mason MD (2009) A systematic review and meta-analysis of randomised trials of neo-adjuvant hormone therapy for localised and locally advanced prostate carcinoma. Cancer Treat Rev 35:9–17

    Article  CAS  PubMed  Google Scholar 

  • Stephenson AJ, Kattan MW, Eastham JA, Dotan ZA, Bianco FJ Jr, Lilja H, Scardino PT (2006) Defining biochemical recurrence of prostate cancer after radical prostatectomy: a proposal for a standardized definition. J Clin Oncol 24:3973–3978

    Article  CAS  PubMed  Google Scholar 

  • Stephenson AJ, Kattan MW, Eastham JA, Bianco FJ Jr, Yossepowitch O, Vickers AJ, Klein EA, Wood DP, Scardino PT (2009) Prostate cancer-specific mortality after radical prostatectomy for patients treated in the prostate-specific antigen era. J Clin Oncol 27:4300–4305

    Article  PubMed  PubMed Central  Google Scholar 

  • Steuber T, Budäus L, Walz J et al (2011) Radical prostatectomy improves progression-free and cancer-specific survival in men with lymph node positive prostate cancer in the prostate-specific antigen era: a confirmatory study. BJU Int 107:1755–1761

    Article  PubMed  Google Scholar 

  • Thompson IM, Valicenti RK, Albertsen P, Davis BJ, Goldenberg SL, Hahn C, Klein E, Michalski J, Roach M, Sartor O, Wolf JS Jr, Faraday MM (2013) Adjuvant and salvage radiotherapy after prostatectomy: AUA/ASTRO guideline. J Urol 190:441–449

    Article  PubMed  Google Scholar 

  • Touijer K, Eastham JA, Secin FP, Romero Otero J, Serio A, Stasi J, Sanchez-Salas R, Vickers A, Reuter VE, Scardino PT, Guillonneau B (2008) Comprehensive prospective comparative analysis of outcomes between open and laparoscopic radical prostatectomy conducted in 2003 to 2005. J Urol 179:1811–1817

    Article  PubMed  PubMed Central  Google Scholar 

  • Touijer KA, Mazzola CR, Sjoberg DD, Scardino PT, Eastham JA (2013) Long-term outcomes of patients with lymph node metastasis treated with radical prostatectomy without adjuvant androgen-deprivation therapy. Eur Urol 65:20–25 (Epub vor Druck)

    Article  PubMed  Google Scholar 

  • Twelker L, Fröhner M, Oehlschläger S, Leike S, Wirth M (2007) Komplikationen bei retropubischer radikaler Prostatektomie bei Patienten über 70 Jahre. Urologe [A]; 46 (Suppl. 1):S 42 [Abstract].

    Google Scholar 

  • Uchida T, Shoji S, Nakano M, Hongo S, Nitta M, Usui Y, Nagata Y (2011) High-intensity focused ultrasound as salvage therapy for patients with recurrent prostate cancer after external beam radiation, brachytherapy or proton therapy. BJU Int 107:378–382

    Article  PubMed  Google Scholar 

  • Valerio M, Ahmed HU, Emberton M, Lawrentschuk N, Lazzeri M, Montironi R, Nguyen PL, Trachtenberg J, Polascik TJ (2013) The role of focal therapy in the management of localised prostate cancer: a systematic review. Eur Urol 44:1–20 (Epub vor Druck)

    Google Scholar 

  • Vickers AJ, Bianco FJ, Gonen M, Cronin AM, Eastham JA, Schrag D, Klein EA, Reuther AM, Kattan MW, Pontes JE, Scardino PT (2008) Effects of pathologic stage on the learning curve for radical prostatectomy: evidence that recurrence in organ-confined cancer is largely related to inadequate surgical technique. Eur Urol 53:960–966

    Article  PubMed  PubMed Central  Google Scholar 

  • Wilt TJ, Brawer MK, Jones KM, Barry MJ, Aronson WJ, Fox S, Gingrich JR, Wei JT, Gilhooly P, Grob BM, Nsouli I, Iyer P, Cartagena R, Snider G, Roehrborn C, Sharifi R, Blank W, Pandya P, Andriole GL, Culkin D, Wheeler T, Prostate Cancer Intervention versus Observation Trial (PIVOT) Study Group (2012) Radical prostatectomy versus observation for localized prostate cancer. N Engl J Med 367:203–213

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wirth MP, Froehner M (2013) Radical prostatectomy at young age. BJU Int (im Druck)

    Google Scholar 

  • Wirth M, Fröhner M (2013) Therapie des lokal begrenzten Prostatakarzinoms. In: Rübben H (Hrsg) Uroonkologie, 6. Aufl. Springer Medizin Verlag, Heidelberg (im Druck)

    Google Scholar 

  • Wirth MP, Weissbach L, Marx FJ, Heckl W, Jellinghaus W, Riedmiller H, Noack B, Hinke A, Froehner M (2004) Prospective randomized trial comparing flutamide as adjuvant treatment versus observation after radical prostatectomy for locally advanced, lymph node-negative prostate cancer. Eur Urol 45:267–270

    Article  CAS  PubMed  Google Scholar 

  • Wirth MP, Hakenberg OW, Froehner M (2007a) Optimal treatment of locally advanced prostate cancer. World J Urol 25:169–176

    Article  PubMed  Google Scholar 

  • Wirth M, Tyrrell C, Delaere K, Sánchez-Chapado M, Ramon J, Wallace DM, Hetherington J, Pina F, Heyns CF, Navani S, Armstrong J (2007b) Bicalutamide (Casodex) 150 mg plus standard care in early non-metastatic prostate cancer: results from Early Prostate Cancer Trial 24 at a median 7 years' follow-up. Prostate Cancer Prostatic Dis 10:87–93

    Article  CAS  PubMed  Google Scholar 

  • Wirth, M., L. Weißbach, R. Ackermann, W. Alberti and et al. (2011). Interdisziplinäre Leitlinie der Qualität S3 zur Früherkennung, Diagnose und Therapie der verschiedenen Stadien des Prostatakarzinoms, Deutsche Gesellschaft für Urologie e. V

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Klinik und Poliklinik für Urologie, Universitätsklinikum Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland

    Manfred Wirth

  2. Klinik für Urologie, Universitätsklinikum Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland

    Michael Fröhner

  3. Klinik und Poliklinik für Strahlentherapie und Radioonkologie, Universitätsklinikum Carl Gustav Carus, TU Dresden, Dresden, Deutschland

    Michael Baumann & Tobias Hoelscher

  4. OncoRay – Nationales Zentrum für Strahlenforschung in der Onkologie, Medizinische Fakultät und Universitätsklinikum Carl Gustav Carus, TU Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland

    Michael Baumann & Tobias Hoelscher

Authors
  1. Manfred Wirth
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Michael Fröhner
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Michael Baumann
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Tobias Hoelscher
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Manfred Wirth .

Editor information

Editors and Affiliations

  1. Universitätsklinikum Mannheim, Klinik für Urologie, Mannheim, Baden-Württemberg, Germany

    Maurice Stephan Michel

  2. Klinik für Urologie, Universitätsklinik Mannheim, Mainz, Germany

    Joachim W. Thüroff

  3. Abt. für Urologie, Universitätsklinikum Salzburg, Salzburg, Austria

    Günther Janetschek

  4. Klinik und Poliklinik für Urologie, Univer Tech Univ Dresden, Dresden, Germany

    Manfred Wirth

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Wirth, M., Fröhner, M., Baumann, M., Hoelscher, T. (2016). Prostatakarzinom: Kurative Therapie. In: Michel, M., Thüroff, J., Janetschek, G., Wirth, M. (eds) Die Urologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-39940-4_143

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-39940-4_143

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-39939-8

  • Online ISBN: 978-3-642-39940-4

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation