Zusammenfassung
Die Lutealphase hängt im Wesentlichen von der vorangehenden Follikelphase und der (stattgehabten) Ovulation ab. Die hormonelle Kontrolle der ovariellen Funktion durch die Gonadotropine follikelstimulierendes Hormon (FSH) und luteinisierendes Hormon (LH) spielt eine Schlüsselrolle im physiologischen Prozess des Wachstums, der Entwicklung sowie der Differenzierung von Follikeln. Grundlage für das Verständnis der Follikel- und Lutealphase ist die “two cell, two gonadotropin theory” (Short 1962). Sie besagt zum einen, dass eine räumliche Unterteilung und Abschottung der Aktivität der Steroidhormonsynthese in den sich entwickelnden Follikeln besteht und zum anderen, dass sowohl FSH als auch LH essenziell für die Follikelreifung und die Synthese ovarieller Steroidhormone sind (Short 1962).
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Wallwiener, LM., Toth, B. (2014). Follikelreifungsstörung und Corpus-luteum-Insuffizienz. In: Gnoth, C., Mallmann, P. (eds) Perikonzeptionelle Frauenheilkunde. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38023-5_27
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