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Molecular Concentration Profiling in the Skin Using Confocal Raman Spectroscopy

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Textbook of Aging Skin

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Abstract

The uppermost layer of the skin – the stratum corneum (SC) – plays a vital role in the functioning and protection of the human body. It provides mechanical protection and regulates water movement in and out. Despite the relatively small dimensions of the SC over most of the body parts (its thickness is of the order of 20 μm over a large portion of the body), it is far from a homogeneous structure both physically and chemically. Chemical concentrations change from its surface inward, and these changes are responsible for both the properties it possesses and the processes occurring within it. Furthermore, with the application of topical cosmetic products becoming more popular and widespread, especially in the antiaging market, the monitoring of ingredients that are capable of penetrating into the skin from the outside, which may also influence the processes occurring within and properties of the SC, is now a necessity.

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Authors and Affiliations

  1. Procter & Gamble, Greater London Innovation Centre, Egham, Surrey, UK

    Paul J. Matts

  2. JMC Scientific Consulting Ltd, Surrey, UK

    Jonathan M. Crowther

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  1. Jonathan M. Crowther
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  2. Paul J. Matts
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Correspondence to Paul J. Matts .

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Editors and Affiliations

  1. Procter & Gamble Co., Cincinnati, Ohio, USA

    Miranda A. Farage

  2. Procter & Gamble Co., Cincinnati, Ohio, USA

    Kenneth W. Miller

  3. Department Dermatology, University of California, San Francisco School of Medicine, San Francisco, California, USA

    Howard I. Maibach

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Crowther, J.M., Matts, P.J. (2015). Molecular Concentration Profiling in the Skin Using Confocal Raman Spectroscopy. In: Farage, M., Miller, K., Maibach, H. (eds) Textbook of Aging Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27814-3_71-2

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  • DOI: https://doi.org/10.1007/978-3-642-27814-3_71-2

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