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Effects of Adenosine Receptors

Drug Discovery and Evaluation: Pharmacological Assays

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Abstract

Adenosine, a purine nucleoside catabolite of ATP, regulates numerous effects in mammalian organ systems. The discovery by Drury and Szent-György (1929) that adenosine can affect several bodily functions inspired much research interest. Regulatory functions of adenosine are especially important when cellular energy supply fails to meet the demand. Adenosine is omnipresent; it is released by nearly all cells and is continuously formed intracellularly as well as extracellularly.

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References and Further Reading

Adenosine A1 Receptor Binding

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    Michael Gralinski, Liomar A. A. Neves & Olga Tiniakova

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Gralinski, M., Neves, L.A.A., Tiniakova, O. (2015). Effects of Adenosine Receptors. In: Hock, F. (eds) Drug Discovery and Evaluation: Pharmacological Assays. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27728-3_140-1

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    Adenosine Receptors
    Published:
    24 February 2015

    DOI: https://doi.org/10.1007/978-3-642-27728-3_140-2

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    Effects of Adenosine Receptors
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    05 February 2015

    DOI: https://doi.org/10.1007/978-3-642-27728-3_140-1

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