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Ultrafiltration Failure

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Nolph and Gokal's Textbook of Peritoneal Dialysis

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Abstract

Ultrafiltration failure is one of the most important complications of peritoneal dialysis (PD). It is seen more frequently in patients treated with PD for a longer period of time, especially when residual urine production is absent. Ultrafiltration failure often leads to overhydration, which is probably the most important cause of cardiovascular death in PD patients. This chapter describes the mechanism of fluid transport during peritoneal dialysis and discusses the proper definition of ultrafiltration failure. It summarizes a variety of causes of homeostasis failure and practical guidelines are presented to make an appropriate diagnosis. The possible therapeutical measures are discussed extensively. Special interest is given to prevention of fluid overload in PD patients and in addition prospects for the future are debated.

This chapter is an update and modification of chapter 17 by S. Mujais and W. Smit published in the 3rd. edition.

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Authors and Affiliations

  1. Department of Internal Medicine, Jeroen Bosch Hospital, ‘s-Hertogenbosch, The Netherlands

    Watske Smit

  2. Division of Nephrology, Academic Medical Center – University of Amsterdam, Amsterdam, The Netherlands

    Raymond T. Krediet

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  1. Watske Smit
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  2. Raymond T. Krediet
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Correspondence to Raymond T. Krediet .

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  1. Nephrology, School of Medicine Department of Medicine Division of, Columbia, MO, USA

    Ramesh Khanna

  2. Dept. Medicine Div. Nephrology, University of Amsterdam Academic Medical Center, Amsterdam, The Netherlands

    Raymond T. Krediet

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Smit, W., Krediet, R.T. (2022). Ultrafiltration Failure. In: Khanna, R., Krediet, R.T. (eds) Nolph and Gokal's Textbook of Peritoneal Dialysis. Springer, Cham. https://doi.org/10.1007/978-3-319-90760-4_17-1

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