Abstract
The research atrocities committed during World War II using human subjects prompted the development of a body of regulations, beginning with the Nuremberg Code, to ensure that human subjects’ research is safely conducted and prioritizes the rights of the individual over the conduct of the research. The resultant regulations guiding human subjects’ research affect protocol design, the selection of participants, safety reporting and oversight, and the dissemination of research results. The investigator conducting research on human subjects must be familiar with those regulations to meet his/her responsibility to protect the rights and welfare of research participants.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Baer AR, Devine S, Beardmore CD, Catalano R (2011) Clinical investigator responsibilities. J Oncol Pract 7:124–128. https://doi.org/10.1200/JOP.2010.000216
Emanuel EJ, Wendler D, Grady C (2000) What makes clinical research ethical? JAMA 283:2701–2711. https://doi.org/10.1001/jama.283.20.2701
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Section Editor information
Rights and permissions
Copyright information
© 2022 Springer Nature Switzerland AG
About this entry
Cite this entry
Giantonio, B.J. (2022). Investigator Responsibilities. In: Piantadosi, S., Meinert, C.L. (eds) Principles and Practice of Clinical Trials. Springer, Cham. https://doi.org/10.1007/978-3-319-52636-2_29
Download citation
DOI: https://doi.org/10.1007/978-3-319-52636-2_29
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-52635-5
Online ISBN: 978-3-319-52636-2
eBook Packages: Mathematics and StatisticsReference Module Computer Science and Engineering