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Current Imaging: PET Scan Use in Cerebral Palsy

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Cerebral Palsy

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Abstract

Cerebral palsy (CP) is a heterogeneous group of disorders of movement and posture due to a defect, injury, or lesion of the immature brain during the antenatal, natal, or early postnatal period. The major types of cerebral palsy include spastic, extrapyramidal, and mixed cerebral palsy. Prematurely born babies most commonly have the spastic diplegic type of CP. When one hemisphere is affected, spastic hemiplegic CP may occur. There have been radical changes in our understanding of the etiology of CP over the past several decades due to rapid advances in neurogenetics and the advent of neuroimaging tools including cranial ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), and newer advanced imaging modalities such as diffusion tensor imaging (DTI). The use of MRI has revolutionized the capacity of clinicians to obtain detailed images of the brain neonatally (even prenatally) and in the investigation of CP. Used in combination with history and clinical examination, the neuroimaging studies play a pivotal role in elucidating the etiology and pathogenesis of CP.

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Authors and Affiliations

  1. Nemours/Alfred I. duPont Hospital for Children, Nemours Neuroscience Center, Wilmington, DE, USA

    Sreenath Thati Ganganna

  2. NYU Comprehensive Epilepsy Center, Department of Neurology, NYU School of Medicine, New York, NY, USA

    Harry T. Chugani

Authors
  1. Sreenath Thati Ganganna
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  2. Harry T. Chugani
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Corresponding author

Correspondence to Sreenath Thati Ganganna .

Editor information

Editors and Affiliations

  1. Alfred I. duPont Institute, Wilmington, DE, USA

    Freeman Miller

  2. Cerebral Palsy Program, AI DuPont Hospital for Children , Wilmington, DE, USA

    Steven Bachrach

  3. AI DuPont Hospital for Children , Wilmington, DE, USA

    Nancy Lennon

  4. Drexel University, PHILADELPHIA, PA, USA

    Margaret O'Neil

Section Editor information

  1. Nemours Alfred I. DuPont Hospital for Children, Wilmington, DE, USA

    Freeman Miller

  2. Department of Pediatrics (Emeritus), Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE, USA

    Steven J. Bachrach

  3. Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA

    Steven J. Bachrach

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Ganganna, S.T., Chugani, H.T. (2019). Current Imaging: PET Scan Use in Cerebral Palsy. In: Miller, F., Bachrach, S., Lennon, N., O'Neil, M. (eds) Cerebral Palsy. Springer, Cham. https://doi.org/10.1007/978-3-319-50592-3_11-1

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  • DOI: https://doi.org/10.1007/978-3-319-50592-3_11-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-50592-3

  • Online ISBN: 978-3-319-50592-3

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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