Teaser
“Will systems biology come to play a role in all future sciences, analogous to the role that Newton’s classical physics played across the entire range of other sciences? I think that systems biology has the potential to influence thinking in all sciences as well as the way we think about societal issues. Shifting from the input/output and complicated system paradigm to the complex multilevel system paradigm also provides a basis for better understanding how financial systems function, or ought to function. The world is multilevel: from global to local, from resources and environment to high finance and politics etc. We therefore need new theoretical frameworks for dealing with complex phenomena. I believe the time is right for a wakeup call.”
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Notes
- 1.
Angiogenesis is a tissue forming process which originally was discovered as a prerequisite for cancer progression but has been identified in a number of other physiological processes as well, including wound healing, growth of neurons in the brain etc.
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Suggested Readings by Mihajlo Mesarović
Mesarović, M. (1968). Systems theory and biology – View of a theoretician. In M. Mesarović (Ed.), Systems theory and biology. Proceedings of the III systems symposium at case institute of technology (pp. 57–87). New York: Springer.
Mesarović, M., & Takahara, Y. (1975). General systems theory: Mathematical foundations. New York: Academic.
Mesarović, M., Sreenath, S. N., & Keene, J. D. (2004). Search for organizing principles: Understanding in systems biology. Systems Biology, 1, 19–27.
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Mesarović, M. (2017). Complexity Organizing Principles: Prerequisites for Life. In: Green, S. (eds) Philosophy of Systems Biology. History, Philosophy and Theory of the Life Sciences, vol 20. Springer, Cham. https://doi.org/10.1007/978-3-319-47000-9_19
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