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Adhesives and Glues

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Kanerva’s Occupational Dermatology

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Abstract

Exposure to adhesives and glues is common in occupation, leisure time, and household activities. There is a constantly growing group of occupational glues in which the adhesive is a polymerization product formed by a complex chemical reaction between the macromolecules.

Phenol-formaldehyde resins have occupational relevance for shoemakers, in car manufacturing, in the wood industries, and in construction industries.

Epoxy resins, used in a wide range of industries, penetrate regular gloves and may cause aerogenic contact dermatitis.

While acrylic adhesives are less sensitizing than epoxy and colophony rosin, acrylates present with cross-reactions among each other, but not between methacrylates and cyanoacrylates.

Colophony rosin is a natural material and also used in many occupational fields.

Glues should be tested epicutaneously either using commercial patch-test substances or as is but only after having completely dried in order to minimize the risk of active sensitization via patch testing.

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References

  • Aalto-Korte K, Alanko A, Kuuliala O, Jolanki J (2008) Occupational methacrylate and acrylate allergy from glues. Contact Dermatitis 58:340–346

    Article  CAS  Google Scholar 

  • Aalto-Korte K, Jungewelter S et al (2009) Contact allergy to epoxy methacrylates. Contact Dermatitis 61:9–21

    Article  CAS  Google Scholar 

  • Angelini E, Marinaro C, Carrozzo AM et al (1993) Allergic contact dermatitis of the lip margins from para-tertiary-butylphenol in a lip liner. Contact Dermatitis 28:146–148

    Article  CAS  Google Scholar 

  • Belsito DV (1987) Contact dermatitis to ethyl-cyanoacrylate-containing glue. Contact Dermatitis 17:234–236

    Article  CAS  Google Scholar 

  • Bruze M, Bjoerkner B, Lepoittevin JP (1995) Occupational allergic contact dermatitis from ethyl cyanoacrylate. Contact Dermatitis 32:156–159

    Article  CAS  Google Scholar 

  • De Groot AC, Bruynzeel DP, Bos JD et al (1988) The allergens in cosmetics. Arch Dermatol 124:1525–1529

    Article  Google Scholar 

  • Elms J, Fishwick D, Robinson E, Burge S, Huggins V, Barber C, Williams N, Curran A (2005) Specific IgE to colophony? Occup Med (Lond) 55(3):234–237

    Article  Google Scholar 

  • Fowler JF, Skinner SM, Belsito DV (1992) Allergic contact dermatitis from formaldehyde resins in permanent press clothing: an under diagnosed cause of generalized dermatitis. J Am Acad Dermatol 27:962–968

    Article  Google Scholar 

  • Freeman S (1997) Shoe dermatitis. Contact Dermatitis 36:247–251

    Article  CAS  Google Scholar 

  • Fregert S, Orsmark K (1984) Allergic contact dermatitis due to epoxy resin in textile labels. Contact Dermatitis 11:131–132

    Article  CAS  Google Scholar 

  • Gambichler T, Boms S, Freitag M (2004) Contact dermatitis and other skin conditions in instrumental musicians. BMC Dermatol 4:3

    Article  Google Scholar 

  • Geldof BA, Roesyanto ID, van Joost T (1989) Clinical aspects of para-tertiary butylphenol formaldehyde resin (PTBP-FR) allergy. Contact Dermatitis 21:312–315

    Article  CAS  Google Scholar 

  • Guin JD (1995) Colophony (rosin). In: Practical contact dermatitis. McGraw-Hill, New York, pp 115–124

    Google Scholar 

  • Guin JD, Baas K, Nelson-Adesokan P (1998) Contact sensitization to cyanoacrylate adhesive as a cause of severe onychodystrophy. Int J Dermatol 37:31–36

    Article  CAS  Google Scholar 

  • Hagvall L, Niklasson IB, Rudbäck J, O’Boyle NM, Niklasson E, Luthman K, Karlberg AT (2016) Assessment of cross-reactivity of new less sensitizing epoxy resin monomers in epoxy resin-allergic individuals. Contact Dermatitis 75:144–150

    Article  CAS  Google Scholar 

  • Hausen BM, Kulenkamp D (1998) Allergische kontaktdermatitis auf einem hydrokolloidverband bei kolophoniumallergikern. Aktuel Dermatol 24:174–177

    Google Scholar 

  • Hausen BM, Milbrodt M, Koenig WA (1995) The allergens of nail polish. Contact Dermatitis 33:157–164

    Article  CAS  Google Scholar 

  • Holness DL, Nethercott JR (1989) Occupational contact dermatitis due to epoxy resin in a fiberglass binder. J Occup Med 31:87–89

    CAS  PubMed  Google Scholar 

  • Jones K, Garfit SJ, Calverley A, Channa K, Cocker J (2001) Identification of a possible biomarker for colophony exposure. Occup Med (Lond) 51(8):507–509

    Article  CAS  Google Scholar 

  • Jordan WP (1975) Cross-sensitization patterns in acrylate allergies. Contact Dermatitis 1:13–15

    Article  Google Scholar 

  • Kanerva L, Alanko K (1998) Allergic contact dermatitis from 2-hydroxy methacrylate in an adhesive of an electrosurgical grounding plate. Eur J Dermatol 8(7)521–4

    Google Scholar 

  • Kanerva L, Estlander T (2000) Allergic onycholysis and paronychia caused by cyanoacrylate nail glue, but not by photobonded methacrylate nails. Eur J Dermatol 10(3):223–225

    CAS  PubMed  Google Scholar 

  • Kanerva L, Jolanki R, Leino T, Estlander T (1995) Occupational allergic contact dermatitis from 2-hydroxyethyl methacrylate and ethylene glycol dimethacrylate in a modified acrylic structural adhesive. Contact Dermatitis 33:84–89

    Article  CAS  Google Scholar 

  • Kiec-Swierczynska M, Krecisz B, Swiercynska-Machura D, Zaremba J (2005) An epidemic of occupational contact dermatitis from an acrylic glue. Contact Dermatitis 52(3):121–125

    Article  CAS  Google Scholar 

  • Kober BJ, Scheule AM, Voth V, Deschner N, Schmid E, Ziemer G (2008) Anaphylactic reaction after systemic application of aprotinin triggered by aprotinin-containing fibrin sealant. Anaesth Analg 107(2):406–409

    Article  Google Scholar 

  • Kopferschmidt-Kubler MC, Stenger R, Blaumeiser M et al (1996) Asthma, rhinitis and urticaria following occupational exposure to cyanoacrylate glues. Rev Mal Respir 13:305–307

    Google Scholar 

  • Lachapelle JM, Leroy B (1990) Allergic contact dermatitis to colophony included in the formulation of flexible collodion BP, the vehicle of a salicylic and lactic acid wart paint. Dermatol Clin 8:143–146

    CAS  PubMed  Google Scholar 

  • Lazarov A (2007) Sensitization to acrylates is a common adverse reaction to artificial fingernails. J Eur Acad Dermatol Venereol 21:169–174

    Article  CAS  Google Scholar 

  • Lombardi C, Botello M, Caruso A, Passalacqua G (2003) Allergy and skin diseases in musicians. Eur Ann Allergy Clin Immunol 35(2):52–55

    CAS  PubMed  Google Scholar 

  • Malten KE (1984) Dermatological problems with synthetic resins and plastics in glues, Part I. Dermatosen 32:81–86

    CAS  Google Scholar 

  • Manusco G, Reggiani M, Berdondini RM (1996) Occupational dermatitis in shoemakers. Contact Dermatitis 34:17–22

    Article  Google Scholar 

  • O’Boyle NM, Delaine T, Luthman K, Natsch A, Karlberg AT (2012) Analogues of the epoxy resin monomer diglycidyl ether of bisphenol F: effects on contact allergenic potency and cytotoxicity. Chem Res Toxicol 25:2469–2478

    Article  Google Scholar 

  • Ockenfels HM, Seemann U, Goos M (1995) Allergy to fibrin tissue in dental medicine. Contact Dermatitis 32:363–364

    Article  CAS  Google Scholar 

  • Pesonen M, Jolanki R, Larese Filon F, Wilkinson M, Kręcisz B, Kieć-Świerczyńska M, Bauer A, Mahler V, John SM, Schnuch A, Uter W, ESSCA network (2015) Patch test results of the European baseline series among patients with occupational contact dermatitis across Europe – analyses of the European Surveillance System on Contact Allergy network, 2002–2010. Contact Dermatitis 72:154–163

    Article  CAS  Google Scholar 

  • Quirce S (2004) Eosinophilic bronchitis in the workplace. Curr Opin Allergy Clin Immunol 4(2):87–91

    Article  Google Scholar 

  • Richter G (1974) Zur epidemiologie des epoxidharzekzems. Dermatol Monatsschr 160:785–789

    CAS  PubMed  Google Scholar 

  • Sadhra S, Foulds IS, Gray CN et al (1997) Colophony uses, health effects, airborne measurement and analysis. Ann Occup Hyg 38:385–396

    Google Scholar 

  • Sainio E-L, Engstroem K, Henriks-Eckerman M-L, Kanerva L (1997) Allergenic ingredients in nail polishes. Contact Dermatitis 37:155–162

    Article  CAS  Google Scholar 

  • Sasseville D, Tennstedt D, Lachapelle JM (1997) Allergic contact dermatitis from hydrocolloid dressings. Am J Contact Dermat 8:236–238

    CAS  PubMed  Google Scholar 

  • Savonius B, Keskinen H, Tuppurainen M, Kanerva L (1993) Occupational respiratory disease caused by acrylics. Clin Exp Allergy 23:416–424

    Article  CAS  Google Scholar 

  • Schnuch A, Szliska C, Uter W (2009) Facial allergic contact dermatitis. Data from the IVDK and review of literature. Hautarzt 60:13–21

    Article  CAS  Google Scholar 

  • Schubert H, Agatha G (1979) Zur Allergennatur der para-tert. Butylphenolformaldehydharze. Dermatosen 27:49–52

    CAS  Google Scholar 

  • Shirai T, Shimota H, Chida K, Sano S, Takeuchi Y, Yasueda H (2005) Anaphylaxis to aprotinin in fibrin sealant. Intern Med 44(10):1088–1089

    Article  Google Scholar 

  • Sripaiboonkij P et al (2009) Respiratory and skin health among glass microfiber production workers: a cross sectional study. Environ Health 8:36

    Article  Google Scholar 

  • Steen VD (1999) Occupational scleroderma. Curr Opin Rheumatol 11(6):490–494

    Article  CAS  Google Scholar 

  • Tarvainen K (1995) Analysis of patients with allergic patch test reactions to a plastics and glue series. Contact Dermatitis 32:346–351

    Article  CAS  Google Scholar 

  • Tosti A, Guerra L, Vincenzi C, Peluso AM (1993) Occupational skin hazards from synthetic plastics. Toxicol Ind Health 9:493–502

    Article  CAS  Google Scholar 

  • van Putten PB, Coenraads PJ, Nater J (1984) Hand dermatoses and contact allergic reactions in construction workers exposed to epoxy resins. Contact Dermatitis 10:146–150

    Article  Google Scholar 

  • White IR (1990) Hand eczema. Occup Health (Lond). 42(11):322–4, 326

    Google Scholar 

  • Wuethrich B, Bianchi Kusch E, Johansson SG (1996) Allergic urticaria and angioedema caused by a hemostatic sponge of bovine fibrin used in tooth extraction. Allergy 51:49–51

    Article  Google Scholar 

  • Yamakage A, Ishikawa H, Saito Y, Hattori A (1980) Occupational scleroderma-like disorder occurring in men engaged in the polymerization of epoxy resins. Dermatologica 161:33–44

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Dermatology, University Hospital Jena, Jena, Germany

    Judit Lukács, Jana Präßler, Matthias Gebhardt & Peter Elsner

Authors
  1. Judit Lukács
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  2. Jana Präßler
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  3. Matthias Gebhardt
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  4. Peter Elsner
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Corresponding author

Correspondence to Peter Elsner .

Editor information

Editors and Affiliations

  1. Department of Dermatology, University of Osnabrück, Osnabrück, Niedersachsen, Germany

    Swen Malte John

  2. Department of Dermato-allergology, Gentofte Hospital, Hellerup, Denmark

    Jeanne Duus Johansen

  3. Dept. of Dermatology and Allergology, VU University Medical Centre, Amsterdam, The Netherlands

    Thomas Rustemeyer

  4. Dept. of Dermatology and Allergology, Friedrich Schiller University, Jena, Thüringen, Germany

    Peter Elsner

  5. Department of Dermatology, University of California San Francisco, San Francisco, California, USA

    Howard I. Maibach

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Lukács, J., Präßler, J., Gebhardt, M., Elsner, P. (2018). Adhesives and Glues. In: John, S., Johansen, J., Rustemeyer, T., Elsner, P., Maibach, H. (eds) Kanerva’s Occupational Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-40221-5_59-2

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  • DOI: https://doi.org/10.1007/978-3-319-40221-5_59-2

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  • Print ISBN: 978-3-319-40221-5

  • Online ISBN: 978-3-319-40221-5

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